Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.40 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4354003 | 1.00 | RPS6KB1 (0.45) | RPS6KB1GSK3BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2908444 | 0.92 | PDE10A (0.45) | RPS6KB1GSK3BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL90572 | 0.92 | PDE10A (0.45) | RPS6KB1GSK3BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2910280 | 0.92 | PDE10A (0.45) | RPS6KB1GSK3BSLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL27510131 | 0.90 | GSK3B (0.45) | RPS6KB1GSK3BSLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL10626673 | 0.90 | GSK3B (0.45) | RPS6KB1GSK3BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2913625 | 0.89 | SLC6A2 (0.40) | RPS6KB1GSK3BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27765904 | 0.89 | SLC6A2 (0.46) | RPS6KB1GSK3BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2911012 | 0.87 | NAPEPLD (0.41) | RPS6KB1GSK3BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27744984 | 0.86 | L3MBTL1 (0.42) | RPS6KB1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275749-A1 | PRODUCTION METHOD OF OPTICALLY ACTIVE PIPERAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-11-05 | — | — | US | disclosed |
| EP-1930325-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE PIPERAZINE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275749-A1 | PRODUCTION METHOD OF OPTICALLY ACTIVE PIPERAZINE COMPOUND | CYP51A1, CYP4Z1, CYP4A11 | SLC6A4 113/4885RPS6KB1 502/4885GSK3B 876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.