SCHEMBL29136420

SCHEMBL29136420

CC(=O)c1cn([C@]2(C)O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.41
CYP2C9 P11712 2/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.39
CYP2C19 P33261 4/20 0.38
CYP1A2 P05177 3/20 0.38
MEN1 O00255 2/20 0.38
GAA P10253 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PYGM P11217 3/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18132293 0.91 PYGM (0.38) PYGM
SCHEMBL15122726 0.89 PYGM (0.35) PYGM
SCHEMBL157466 0.87 KDM4E (0.34) GAAPYGM
SCHEMBL1825757 0.84 TK1 (0.43) ALDH1A1
SCHEMBL12658380 0.84 TK1 (0.43) ALDH1A1
SCHEMBL26666707 0.84 PYGM (0.38) PYGM
SCHEMBL6829243 0.83 PYGM (0.37) PYGM
SCHEMBL6537910 0.83 LMNA (0.46) MAPTPYGM
SCHEMBL29188115 0.81 TK2 (0.36) PYGM
SCHEMBL7262195 0.81 PYGM (0.36) PYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119604311-A FN3 domain-siRNA conjugates and enzyme replacement therapies ARO生物疗法公司 2025-03-11 CN disclosed
CN-117242184-A Guide RNA design and complexes for V-type Cas systems 地平线探索有限公司 2023-12-15 CN disclosed
CN-117222743-A Guide RNA design and complexes for Tracr-free V-Cas systems 地平线探索有限公司 2023-12-12 CN disclosed