Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.37 |
| ▸ | PYGB | P11216 | 1/20 | 0.35 |
| ▸ | TK2 | O00142 | 2/20 | 0.34 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.34 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TK1 | P04183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28230285 | 0.88 | PYGB (0.34) | PYGMPYGBSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL27900813 | 0.88 | PYGB (0.34) | PYGMPYGB | |
| SCHEMBL1825757 | 0.86 | TK1 (0.43) | TK2LMNATK1 | |
| SCHEMBL26666707 | 0.86 | PYGM (0.38) | PYGMTK2SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL12658380 | 0.86 | TK1 (0.43) | TK2LMNATK1 | |
| SCHEMBL6537910 | 0.85 | LMNA (0.46) | PYGMTK2LMNASMN1; SMN2 | |
| SCHEMBL15122726 | 0.84 | PYGM (0.35) | PYGMPYGBTK2LMNASMN1; SMN2 | |
| SCHEMBL7262195 | 0.83 | PYGM (0.36) | PYGMTK2LMNASMN1; SMN2TK1 | |
| SCHEMBL29136420 | 0.83 | KMT2A (0.41) | PYGM | |
| SCHEMBL6829048 | 0.83 | PYGM (0.36) | PYGMPYGBTK2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110505877-A | RNA cancer vaccine | MODERNATX INC | 2019-11-26 | — | — | CN | disclosed |
| CN-109640962-A | POLYNUCLEOTIDES ENCODING RELAXIN | 摩登纳特斯有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109476718-A | Combination of MRNA encoding immunomodulatory polypeptides and uses thereof | 莫得纳特斯公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-109195621-A | Polynucleotides encoding interleukin 12(IL12) and uses thereof | 莫得纳特斯公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-108472355-A | HSV vaccine | 摩登纳特斯有限公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108472309-A | Nucleic acid vaccine for Varicella Zoster Virus (VZV) | 摩登纳特斯有限公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108430456-A | Cancer vaccine | 摩登纳特斯有限公司 | 2018-08-21 | — | — | CN | disclosed |
| US-20040214198-A1 | Allele-targeted RNA interference | UNIVERSITY OF MASSACHUSETTS | 2004-10-28 | — | — | US | disclosed |
| WO-2004046324-A2 | ALLELE-TARGETED RNA INTERFERENCE | UNIVERSITY OF MASSACHUSETTS (US) | 2004-06-03 | — | — | WO | disclosed |