Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.36 |
| ▸ | TK2 | O00142 | 3/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872134 | 0.88 | PYGB (0.31) | PYGM | |
| SCHEMBL27900812 | 0.88 | PYGM (0.33) | PYGM | |
| SCHEMBL28326624 | 0.87 | PYGM (0.34) | PYGMTK2TK1 | |
| SCHEMBL547489 | 0.85 | TYMP (0.33) | PYGMTK2 | |
| SCHEMBL1825757 | 0.84 | TK1 (0.43) | TK2TK1LMNA | |
| SCHEMBL12658380 | 0.84 | TK1 (0.43) | TK2TK1LMNA | |
| SCHEMBL26666707 | 0.84 | PYGM (0.38) | PYGMTK2TK1LMNASMN1; SMN2 | |
| SCHEMBL9519057 | 0.84 | PYGM (0.34) | PYGMTK2TK1LMNASMN1; SMN2 | |
| SCHEMBL6829243 | 0.83 | PYGM (0.37) | PYGMTK2TK1LMNASMN1; SMN2 | |
| SCHEMBL6537910 | 0.83 | LMNA (0.46) | PYGMTK2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512525-B1 | COMBINATION THERAPY WITH LIPOSOMAL ANTISENSE OLIGONUCLEOTIDES | BIO PATH HOLDINGS INC (US) | 2022-07-27 | — | — | EP | disclosed |
| CN-103917664-A | Nuclease substrates | SPEEDX PTY LTD | 2014-07-09 | — | — | CN | disclosed |
| CN-1906309-B | Marker Lmx1a specific for dopamine-producing neurons | Sanitary Material R&D Management Co.,Ltd. (JP) | 2011-12-14 | — | — | CN | disclosed |
| CN-101932609-A | Compositions and methods for modulating cell membrane resealing | UNIV NEW JERSEY MED | 2010-12-29 | — | — | CN | disclosed |
| CN-101268199-A | Detection of nucleic acid amplification | APPLERA CORP (US) | 2008-09-17 | — | — | CN | disclosed |
| CN-1906309-A | Marker Lmx1a specific for dopamine-producing neurons | EISAI CO LTD (JP) | 2007-01-31 | — | — | CN | disclosed |
| US-6645944-B2 | Antiproliferative and anticarcinogenic agents; gene therapy | ALTON OCHSNER MEDICAL FOUNDATION | 2003-11-11 | — | — | US | disclosed |
| US-20020103153-A1 | Inhibition of cellular proliferation by oligonucleotide binding to a chromosomal binding site for p53 protein | RE RICHARD (US) | 2002-08-01 | — | — | US | disclosed |
| US-6303328-B1 | ANTICARCINOGENIC AGENTS | ALTON OCHSNER MEDICAL FOUNDATION | 2001-10-16 | — | — | US | disclosed |
| US-6124091-A | ANTISENSE NUCLEOTIDES WHICH SUPPRESS EXPRESSION OF A KINASE GENE; FOR EXPANSION OF HEMATOPOIETIC CELLS IN UMBILICAL CORD BLOOD AND STEM CELLS; FOR ACTIVATING NEUTROPHIL EXPANSION IN DEPLETED MARROW CELLS; ANTIPROLIFERATIVE AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-09-26 | — | — | US | disclosed |
| US-5808036-A | Stem-loop oligonucleotides containing parallel and antiparallel binding domains | RESEARCH CORPORATION TECHNOLOGIES INC. (US) | 1998-09-15 | — | — | US | disclosed |
| US-5683874-A | Single-stranded circular oligonucleotides capable of forming a triplex with a target sequence | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-11-04 | — | — | US | disclosed |
| US-5674683-A | BINDING DOMAINS CAPABLE OF DETECTABLY BINDING TO A NUCLEIC ACID TARGET BY WATSON-CRICK BASE PAIRING AND BY HOOGSTEEN BASE PAIRING | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-10-07 | — | — | US | disclosed |
| WO-1996030384-A1 | SINGLE-STRANDED CIRCULAR OLIGONUCLEOTIDES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-10-03 | — | — | WO | disclosed |
| WO-1996029097-A1 | STEM-LOOP AND CIRCULAR OLIGONUCLEOTIDES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-09-26 | — | — | WO | disclosed |
| US-5514546-A | Stem-loop oligonucleotides containing parallel and antiparallel binding domains | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0649411-A4 | BORONATED COMPOUNDS. | BORON BIOLOG INC (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0649411-A1 | BORONATED COMPOUNDS | BORON BIOLOGICALS, INC. (US) | 1995-04-26 | — | — | EP | disclosed |
| EP-0579771-A1 | SINGLE-STRANDED CIRCULAR OLIGONUCLEOTIDES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992017484-A1 | SINGLE-STRANDED CIRCULAR OLIGONUCLEOTIDES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-10-15 | — | — | WO | disclosed |