SCHEMBL29136785

SCHEMBL29136785

CNc1cn2cc(C3CC3)cc(Cl)c2n1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 2/20 0.33
PDE10A Q9Y233 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29136912 0.84
SCHEMBL29155776 0.82 CYP11B1 (0.30)
SCHEMBL29136867 0.74 NUDT1 (0.41)
SCHEMBL24737385 0.73 KLKB1 (0.33) PDE10A
SCHEMBL29136922 0.71 METTL3 (0.38)
Hydrochloric Acid SCHEMBL29136812 0.70 METTL3 (0.37)
SCHEMBL29277976 0.70 HRH4 (0.32)
SCHEMBL24737332 0.65 TYR (0.41) MAT2A
SCHEMBL24737491 0.63 PPARA (0.31)
SCHEMBL29318485 0.63 KDM4E (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117355521-A Heteroaryl inhibitors of plasma kallikrein 武田药品工业株式会社 2024-01-05 CN disclosed