Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24738056 | 0.81 | ATP4A (0.37) | ATP4AATP4BSTAT3HTTSMN1; SMN2 | |
| SCHEMBL30997838 | 0.76 | ENPP2 (0.35) | GRM2MEN1KMT2A | |
| SCHEMBL24739008 | 0.76 | ENPP2 (0.35) | GRM2MEN1KMT2A | |
| SCHEMBL29879453 | 0.75 | ACHE (0.39) | PDE4APDE4BPDE4CPDE4DPKM | |
| SCHEMBL24738948 | 0.75 | ACHE (0.39) | PDE4APDE4BPDE4CPDE4DPKM | |
| SCHEMBL29302597 | 0.75 | MCHR1 (0.35) | MCHR1STAT3HTTSMN1; SMN2PDE4A | |
| SCHEMBL29136785 | 0.74 | MAT2A (0.33) | — | |
| SCHEMBL29136912 | 0.73 | — | — | |
| SCHEMBL29155776 | 0.72 | CYP11B1 (0.30) | — | |
| SCHEMBL7011291 | 0.70 | HTR1A (0.43) | ATP4AATP4BSMN1; SMN2SLC6A4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |