Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137184 | 0.90 | DRD2 (0.40) | ALDH1A1MAPTDRD2DRD4LMNA | |
| SCHEMBL29137279 | 0.89 | DRD2 (0.43) | ALDH1A1KDM4EMAPTDRD2DRD4 | |
| SCHEMBL30616673 | 0.87 | SIGMAR1 (0.51) | ALDH1A1KDM4EMAPTDRD2DRD4 | |
| SCHEMBL29137283 | 0.85 | DRD4 (0.38) | ALDH1A1MAPTDRD4KCNH2HTR1A | |
| SCHEMBL30616751 | 0.84 | DRD4 (0.42) | ALDH1A1MAPTUSP2HTTCYP3A4 | |
| SCHEMBL30616711 | 0.84 | GRM2 (0.41) | ALDH1A1KDM4EMAPTDRD2DRD4 | |
| SCHEMBL30616757 | 0.83 | SIGMAR1 (0.43) | MAPTDRD4SLC6A4KCNH2HTR1A | |
| SCHEMBL29137229 | 0.83 | TRPC5 (0.48) | ALDH1A1KDM4EMAPTCNR1HTR1A | |
| SCHEMBL30616679 | 0.83 | GRM2 (0.45) | ALDH1A1KDM4EMAPTHTTDRD4 | |
| SCHEMBL30616754 | 0.80 | MEN1 (0.46) | ALDH1A1KDM4EMAPTDRD4SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |