Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30616732 | 0.87 | KDM4E (0.46) | KDM4ELMNAMAPTTNKSPARP1 | |
| SCHEMBL30616746 | 0.85 | GRM2 (0.41) | KDM4ELMNAMAPTTNKSPARP1 | |
| SCHEMBL29137184 | 0.84 | DRD2 (0.40) | LMNATP53MAPTALDH1A1 | |
| SCHEMBL28549345 | 0.84 | KDM4E (0.48) | KDM4ELMNATP53MAPTALDH1A1 | |
| SCHEMBL29137205 | 0.83 | ALDH1A1 (0.49) | KDM4ELMNAMAPTKMT2AMEN1 | |
| SCHEMBL30616705 | 0.83 | TRPC5 (0.39) | TRPC5KDM4EALDH1A1HTR1AHTR1D | |
| SCHEMBL30616722 | 0.82 | GRM2 (0.44) | TRPC5KDM4ELMNAMAPTPARP1 | |
| SCHEMBL30616712 | 0.82 | GRM2 (0.44) | TRPC5KDM4EPARP1ALDH1A1HTR1A | |
| SCHEMBL30616730 | 0.82 | ALDH1A1 (0.46) | TRPC5KDM4EMAPTALDH1A1COMT | |
| SCHEMBL29137283 | 0.81 | DRD4 (0.38) | MAPTKMT2AMEN1ALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |