Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137184 | 0.90 | DRD2 (0.40) | DRD4ALDH1A1GAAMAPTCHRNA7 | |
| SCHEMBL29137279 | 0.90 | DRD2 (0.43) | DRD4ALDH1A1MAPTHTR1ANCF1 | |
| SCHEMBL30616679 | 0.88 | GRM2 (0.45) | DRD4ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30616751 | 0.87 | DRD4 (0.42) | DRD4ALDH1A1MAPTKCNH2MCHR1 | |
| SCHEMBL30616711 | 0.86 | GRM2 (0.41) | DRD4ALDH1A1GAAMAPTKCNH2 | |
| SCHEMBL30616757 | 0.86 | SIGMAR1 (0.43) | DRD4MAPTKCNH2MCHR1HTR1A | |
| SCHEMBL29137205 | 0.85 | ALDH1A1 (0.49) | DRD4ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL30616673 | 0.82 | SIGMAR1 (0.51) | DRD4ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL29137229 | 0.81 | TRPC5 (0.48) | ALDH1A1MAPTMEN1KMT2AHTR1A | |
| SCHEMBL28549345 | 0.81 | KDM4E (0.48) | DRD4ALDH1A1GAAMAPTHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |