Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28671894 | 0.84 | RECQL (0.36) | ALDH1A1MAPTRAB9ANPC1NPSR1 | |
| SCHEMBL379859 | 0.80 | MAPT (0.39) | ALDH1A1EGFRSMN1; SMN2MAPTRAB9A | |
| SCHEMBL943810 | 0.79 | EGFR (0.32) | EGFRMAPTCYP2D6 | |
| SCHEMBL3250625 | 0.70 | MAPT (0.40) | ALDH1A1EGFRPOLBSMN1; SMN2BACE1 | |
| SCHEMBL27988772 | 0.69 | GAA (0.33) | MAPT | |
| SCHEMBL7603455 | 0.67 | EGFR (0.42) | ALDH1A1EGFRSMN1; SMN2MAPTRAB9A | |
| SCHEMBL17338036 | 0.66 | L3MBTL1 (0.35) | ALDH1A1NPC1HSD17B10 | |
| SCHEMBL28056863 | 0.66 | TRPA1 (0.42) | POLBCYP2D6TRPA1HSD17B10 | |
| SCHEMBL1420618 | 0.65 | NOS2 (0.33) | MAPT | |
| SCHEMBL5903655 | 0.65 | GAA (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322157-B | Letermopevir intermediate compound, preparation method and application thereof | 浙江车头制药股份有限公司 | 2023-12-05 | — | — | CN | disclosed |