Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 3/20 | 0.41 |
| ▸ | KDM5C | P41229 | 3/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2041471 | 0.86 | TSHR (0.47) | POLBNAPRTTTRP4HA1CAMKK2 | |
| SCHEMBL29788123 | 0.86 | TSHR (0.47) | POLBNAPRTTTRP4HA1CAMKK2 | |
| SCHEMBL29138051 | 0.85 | AR (0.41) | KDM5CKDM5BARKDRTEK | |
| SCHEMBL29138086 | 0.80 | KDR (0.62) | POLBKDM4EALDH1A1KDRTEK | |
| SCHEMBL4772421 | 0.77 | CAMK2D (0.54) | NAPRTCAMKK2KDM4EALDH1A1 | |
| SCHEMBL940865 | 0.77 | KMO (0.57) | CAMKK2KDM6BKDM4AKDM5CKDM2A | |
| SCHEMBL30285920 | 0.77 | KMO (0.57) | CAMKK2KDM6BKDM4AKDM5CKDM2A | |
| SCHEMBL3994507 | 0.75 | CASP6 (0.38) | — | |
| SCHEMBL29138039 | 0.75 | KDR (0.52) | POLBMAPTKDRTEKKMT2A | |
| SCHEMBL22719341 | 0.74 | JAK2 (0.47) | CAMKK2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343081-A | MAT2A inhibitor, pharmaceutical composition and application thereof | 南京正大天晴制药有限公司 | 2024-01-05 | — | — | CN | disclosed |