Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | TEK | Q02763 | 3/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | MPL | P40238 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138086 | 0.87 | KDR (0.62) | KDRTEKKMT2ANPC1RAB9A | |
| SCHEMBL29138066 | 0.87 | NPC1 (0.51) | KDRTEKROCK2MEN1KMT2A | |
| SCHEMBL29138064 | 0.84 | MPL (0.45) | KDRTEKROCK2NPC1RAB9A | |
| SCHEMBL29138054 | 0.81 | PDE4D (0.45) | KDRTEKROCK2RAB9AMPL | |
| SCHEMBL29138058 | 0.81 | RAB9A (0.58) | KDRTEKMEN1KMT2ANPC1 | |
| SCHEMBL29138090 | 0.81 | MPL (0.44) | KDRTEKMPL | |
| SCHEMBL29138040 | 0.75 | POLB (0.44) | KDRTEKKMT2APOLBMAPT | |
| SCHEMBL20302206 | 0.75 | GRM4 (0.63) | MEN1KMT2APTPN1NPC1RAB9A | |
| SCHEMBL29138051 | 0.74 | AR (0.41) | KDRTEK | |
| SCHEMBL29496075 | 0.73 | GAA (0.81) | MEN1KMT2APTPN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343081-A | MAT2A inhibitor, pharmaceutical composition and application thereof | 南京正大天晴制药有限公司 | 2024-01-05 | — | — | CN | disclosed |