Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875579 | 0.77 | TMPRSS15 (0.49) | SMN1; SMN2TMPRSS15GAANPC1RAB9A | |
| SCHEMBL27361867 | 0.77 | RAB9A (0.49) | SMN1; SMN2TMPRSS15GAANPC1RAB9A | |
| SCHEMBL19520914 | 0.76 | TMPRSS15 (0.49) | SMN1; SMN2TMPRSS15GAANPC1RAB9A | |
| SCHEMBL8305554 | 0.75 | TMPRSS15 (0.48) | SMN1; SMN2TMPRSS15GAANPC1RAB9A | |
| SCHEMBL6632393 | 0.75 | TMPRSS15 (0.55) | SMN1; SMN2TMPRSS15GAANPC1RAB9A | |
| SCHEMBL21525551 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2TMPRSS15GAAS1PR3TDP1 | |
| SCHEMBL29066650 | 0.73 | SMN1; SMN2 (0.60) | SMN1; SMN2GAANPC1RAB9ATSHR | |
| SCHEMBL2586462 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2GAAS1PR3NPC1RAB9A | |
| SCHEMBL2586465 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2GAAS1PR3NPC1RAB9A | |
| SCHEMBL15785411 | 0.72 | GAA (0.53) | SMN1; SMN2GAAS1PR3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355531-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-05 | — | — | CN | disclosed |