Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 9/20 | 0.44 |
| ▸ | NPC1 | O15118 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875579 | 0.82 | TMPRSS15 (0.49) | TMPRSS15MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL27361867 | 0.82 | RAB9A (0.49) | TMPRSS15MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL6632393 | 0.81 | TMPRSS15 (0.55) | TMPRSS15MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL19520914 | 0.78 | TMPRSS15 (0.49) | TMPRSS15MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL27952188 | 0.77 | TMPRSS15 (0.45) | TMPRSS15MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL9566966 | 0.77 | EGFR (0.46) | MAPTRAB9ANPC1ALDH1A1HTT | |
| SCHEMBL23723952 | 0.75 | TMPRSS15 (0.47) | TMPRSS15MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL6650653 | 0.74 | ALDH1A1 (0.58) | TMPRSS15RAB9ANPC1ALDH1A1HTT | |
| SCHEMBL9202062 | 0.74 | ALDH1A1 (0.51) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22978691 | 0.72 | TSHR (0.49) | TMPRSS15MAPTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749429-B1 | 3,5-DISUBSTITUTED AND 3,5,6-TRISUBSTITUTED 2-ISOXAZOLINES AND ISOXAZOLES, PROCESS FOR PREPARING THE SAME AND THEIR USE AS MEDICAMENTS | HOECHST AG (DE) | 1999-06-30 | — | — | EP | disclosed |
| EP-0551821-A1 | Isoxazolecarboxylic acid derivatives and their use as herbicides | BAYER AG (DE) | 1993-07-21 | — | — | EP | disclosed |