SCHEMBL29138467

SCHEMBL29138467

C=CC(=O)NCCc1c(Cc2cccs2)[nH]c2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 5/20 0.51
MTNR1B P49286 5/20 0.51
CYP1A2 P05177 2/20 0.51
CYP3A4 P08684 2/20 0.51
HPGD P15428 2/20 0.51
TSHR P16473 2/20 0.51
CYP2C19 P33261 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CYP2C9 P11712 1/20 0.51
ALOX15 P16050 2/20 0.46
MAPT P10636 2/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP2D6 P10635 1/20 0.46
CHRNB2 P17787 1/20 0.41
CHRNA7 P36544 1/20 0.41
CHRNA4 P43681 1/20 0.41
KCNH2 Q12809 1/20 0.40
HDAC1 Q13547 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9303976 0.86 MTNR1A (0.69) MTNR1AMTNR1BCYP1A2CYP3A4HPGD
SCHEMBL29138489 0.79 MTNR1A (0.60) MTNR1AMTNR1BCYP1A2CYP3A4HPGD
SCHEMBL29138478 0.79 MTNR1A (0.56) MTNR1AMTNR1BCYP1A2CYP3A4HPGD
SCHEMBL26119310 0.76 NPC1 (0.60) HPGDMAPTALDH1A1SMN1; SMN2RAB9A
SCHEMBL9751551 0.72 MTNR1A (0.50) MTNR1AMTNR1BCYP1A2CYP3A4HPGD
SCHEMBL19889076 0.70 KCNH2 (0.58) MTNR1AMTNR1BALOX15KCNH2HDAC1
SCHEMBL29138488 0.69 EGFR (0.47) MTNR1AMTNR1BCYP1A2CYP3A4HPGD
Luzindole SCHEMBL4869000 0.68 MTNR1A (1.00) MTNR1AMTNR1BCYP1A2CYP3A4HPGD
SCHEMBL6668159 0.68 POLB (0.62) HPGDTSHRMEN1KMT2AMAPT
SCHEMBL9401112 0.66 MTNR1A (0.79) MTNR1AMTNR1BCYP1A2CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069645-A Tryptophan and C2 alkylation modification method for tryptophan-containing polypeptide 兰州大学 2023-11-17 CN disclosed