Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086191 | 0.83 | MAPK1 (0.39) | HSD11B1MAPK1AOC3 | |
| SCHEMBL22321307 | 0.77 | ESR2 (0.41) | ESR2HSD11B1DDB1CRBNJAK2 | |
| SCHEMBL1332981 | 0.75 | MAPK1 (0.35) | HSD11B1MAPK1AOC3 | |
| SCHEMBL14734253 | 0.73 | HTR3A (0.41) | MAPK1 | |
| Hydrochloric Acid SCHEMBL30758569 | 0.72 | HTR3A (0.40) | MAPK1 | |
| SCHEMBL17101636 | 0.72 | MAPK1 (0.62) | MAPK1PIM1 | |
| SCHEMBL17101604 | 0.69 | PTGDR2 (0.44) | — | |
| SCHEMBL1739269 | 0.68 | CHRNB2 (0.39) | HSD11B1 | |
| SCHEMBL18965272 | 0.67 | PARP1 (0.39) | HSD11B1PDE9A | |
| SCHEMBL29138584 | 0.67 | MAPK1 (0.37) | HSD11B1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247395-A | PDE4B inhibitors | 武汉人福创新药物研发中心有限公司 | 2023-12-19 | — | — | CN | disclosed |