Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL243227 | 0.82 | CASP1 (0.45) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL6242825 | 0.82 | CASP1 (0.45) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL4211263 | 0.81 | MMP2 (0.46) | NPC1MEN1KMT2ALMNARAB9A | |
| SCHEMBL1140146 | 0.81 | MMP2 (0.46) | NPC1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL19358784 | 0.81 | EPHX1 (0.53) | NPC1HTTMEN1KMT2ALMNA | |
| SCHEMBL10713625 | 0.80 | MMP8 (0.50) | NPC1ALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL4350738 | 0.77 | RAB9A (0.49) | NPC1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6240446 | 0.77 | CA12 (0.51) | NPC1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL11184595 | 0.76 | NPC1 (0.47) | NPC1ALDH1A1POLBHTTMEN1 | |
| SCHEMBL5909869 | 0.75 | NPC1 (0.45) | NPC1ALDH1A1POLBHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-B | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |