Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DUT | P33316 | 3/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320746 | 0.77 | CRBN (0.41) | ALDH1A1LMNADUTCRBNPKM | |
| SCHEMBL5017554 | 0.75 | DUT (0.49) | ALDH1A1LMNADUTCRBNPKM | |
| SCHEMBL8656959 | 0.75 | CRBN (0.48) | ALDH1A1LMNADUTCRBNPKM | |
| SCHEMBL4347792 | 0.75 | CRBN (0.47) | ALDH1A1LMNADUTCRBNPKM | |
| SCHEMBL667245 | 0.74 | ALDH1A1 (0.59) | ALDH1A1LMNADUTCRBNPKM | |
| SCHEMBL954608 | 0.72 | CRBN (0.46) | DUTCRBNPKM | |
| SCHEMBL1046691 | 0.72 | ALDH1A1 (0.37) | ALDH1A1LMNADUTCRBNKDM4E | |
| SCHEMBL30151111 | 0.71 | L3MBTL1 (0.42) | ALDH1A1LMNADUTCRBNPKM | |
| SCHEMBL7548703 | 0.70 | CRBN (0.43) | ALDH1A1LMNADUTCRBNPKM | |
| SCHEMBL665845 | 0.69 | CRBN (0.54) | ALDH1A1LMNADUTCRBNPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791567-A2 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES | Alnylam Pharmaceuticals Inc. (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006020768-A2 | CHEMICALLY MODIFIED OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2006-02-23 | — | — | WO | disclosed |