SCHEMBL2914383

SCHEMBL2914383

OCCCc1cc(Oc2ccccc2)c(O)c(Oc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.50
TNKS2 Q9H2K2 1/20 0.50
POLB P06746 1/20 0.47
LTA4H P09960 2/20 0.45
EPHX2 P34913 1/20 0.45
ALOX5 P09917 1/20 0.41
RHEB Q15382 1/20 0.40
CAMK2A Q9UQM7 1/20 0.39
IGF1R P08069 1/20 0.39
ALOX15 P16050 1/20 0.39
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2914798 0.93 TNKS2 (0.63) TTRTNKS2ALOX5
SCHEMBL9858253 0.91 TTR (0.50) TTRPOLBLTA4HALOX5CAMK2A
SCHEMBL2914322 0.90 TNKS2 (0.48) TTRTNKS2POLBLTA4HEPHX2
SCHEMBL2910800 0.86 TNKS2 (0.44) TTRTNKS2POLBLTA4HEPHX2
SCHEMBL2914006 0.84 F2 (0.56) TTRPOLBLTA4HEPHX2ALOX5
SCHEMBL10984819 0.81 POLB (0.48) TTRPOLBLTA4HALOX5
SCHEMBL9764133 0.80 TTR (0.53) TTRPOLBLTA4HCAMK2A
SCHEMBL2908900 0.80 TNKS2 (0.50) TNKS2ALOX5CYP4F2CYP4A11
SCHEMBL9804282 0.80 TTR (0.46) TTRPOLBLTA4HEPHX2
SCHEMBL18240129 0.77 LTA4H (0.66) LTA4HEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2110370-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-09-01 EP disclosed
EP-1348686-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-03-03 EP disclosed
EP-2110370-A1 Method of producing p-hydroxyphenylalkanols Sumitomo Chemical Company, Limited (JP) 2009-10-21 EP disclosed
US-6717020-B2 HIGH YIELD REACTION OF PHENOLS AND UNSATURATED ALCOHOLS IN PRESENCE OF SUCH AS TITANIUM TETRAETHOXIDE AND SODIUM METHOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-06 US disclosed
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-16 US disclosed
EP-1348686-A1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols ADH1C, NR1H3, ADH5 TTR 2223/4885TNKS2 3493/4885POLB 1363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.