SCHEMBL29140679

SCHEMBL29140679

Nc1cc(N)c(O)nc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 1/20 0.44
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
ALOX15 P16050 4/20 0.33
HSD17B10 Q99714 3/20 0.33
NQO1 P15559 1/20 0.33
CYP3A4 P08684 1/20 0.33
HSP90AA1 P07900 1/20 0.32
HSP90AB1 P08238 1/20 0.32
USP7 Q93009 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
USP2 O75604 1/20 0.32
POLB P06746 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5862327 0.97 PTK2 (0.41) PTK2ALDH1A1MAPTKDM4ELMNA
SCHEMBL13285595 0.75 IDO1 (0.44) ALDH1A1MAPTKDM4EGAAALOX15
SCHEMBL11996546 0.75 MAPT (0.38) ALDH1A1MAPTKDM4ELMNAGAA
Hydrochloric Acid SCHEMBL5862491 0.75 ALOX15 (0.32) ALDH1A1MAPTKDM4ELMNAGAA
SCHEMBL1133368 0.70 ALDH1A1 (0.52) ALDH1A1MAPTKDM4ELMNAGAA
SCHEMBL21609199 0.70 KEAP1 (0.42) ALDH1A1ALOX15HSD17B10HPGDALOX12
SCHEMBL1556612 0.70 NQO2 (0.39) ALDH1A1MAPTKDM4ELMNAGAA
SCHEMBL10348834 0.69 MAPT (0.52) PTK2ALDH1A1MAPTKDM4ELMNA
SCHEMBL25999183 0.67 RIPK1 (0.42) GAAALOX15USP2
SCHEMBL21436872 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114672020-A Preparation method of benzoxazine-based conjugated trapezoidal polymer and application of benzoxazine-based conjugated trapezoidal polymer in hydrogen sulfide detection 天津科技大学 2022-06-28 CN claimed
CN-114672020-B Preparation method of benzoxazinyl conjugated trapezoid polymer and application of benzoxazinyl conjugated trapezoid polymer in hydrogen sulfide detection 天津科技大学 2023-10-20 CN disclosed
CN-114672020-A Preparation method of benzoxazine-based conjugated trapezoidal polymer and application of benzoxazine-based conjugated trapezoidal polymer in hydrogen sulfide detection 天津科技大学 2022-06-28 CN disclosed