Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | ESR1 | P03372 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13286927 | 0.92 | SERPINE1 (0.67) | HTTLMNASMN1; SMN2ESR1NPC1 | |
| SCHEMBL11652623 | 0.82 | SERPINE1 (0.55) | HTTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL23057256 | 0.81 | LMNA (0.73) | HTTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5023540 | 0.81 | HTT (0.73) | HTTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10592845 | 0.81 | LMNA (0.73) | HTTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5024746 | 0.79 | LMNA (0.70) | HTTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL2932439 | 0.79 | LMNA (0.70) | HTTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4069104 | 0.79 | LMNA (0.70) | HTTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL23043651 | 0.79 | LMNA (0.70) | HTTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL3265384 | 0.79 | LMNA (0.70) | HTTLMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222160-B1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD (AU) | 2015-03-18 | — | — | EP | disclosed |
| US-8426587-B2 | Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor | PHARMAXIS LTD. (AU) | 2013-04-23 | — | — | US | disclosed |
| CN-101917845-A | Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor | PHARMAXIS LTD | 2010-12-15 | — | — | CN | disclosed |
| US-20100298330-A1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD. (AU) | 2010-11-25 | — | — | US | disclosed |
| EP-2222160-A2 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | Pharmaxis Ltd. (AU) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009066152-A2 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD. (US) | 2009-05-28 | — | — | WO | disclosed |
| EP-0343604-A2 | Method of forming color images | Fuji Photo Film Co., Ltd. (JP) | 1989-11-29 | — | — | EP | disclosed |
| US-4505929-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1985-03-19 | — | — | US | disclosed |
| EP-0034263-B1 | SUBSTITUTED BENZONITRILES AND COMPOSITIONS FOR INHIBITING VIRUSES | THE DOW CHEMICAL COMPANY (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4349568-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1982-09-14 | — | — | US | disclosed |
| US-4332820-A | ESPECIALLY EFFECTIVE AGAINST PICORNOVIRUSES | THE DOW CHEMICAL COMPANY (US) | 1982-06-01 | — | — | US | disclosed |
| EP-0034263-A2 | Substituted benzonitriles and compositions for inhibiting viruses | THE DOW CHEMICAL COMPANY (US) | 1981-08-26 | — | — | EP | disclosed |
| US-4254144-A | Substituted benzonitriles having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4074059-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-3979203-A | Sulfonamido herbicidal compositions and plant control methods using the same | AMERICAN CYANAMID COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298330-A1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | VAPA, SLC6A11, VAPB | HTT 471/4885LMNA 954/4885SMN1; SMN2 1608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.