SCHEMBL291485

SCHEMBL291485

S=c1[nH]c2cccc3c2n1CCNC3

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 12/20 0.46
HTR2A P28223 4/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
TP53 P04637 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALOX15 P16050 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP2C19 P33261 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HTR1A P08908 2/20 0.43
DRD2 P14416 1/20 0.43
CDK4 P11802 4/20 0.43
CCND1 P24385 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL377396 0.81 HTR1A (0.51) HTR2CHTR2AKDM4EMEN1TP53
SCHEMBL11881460 0.67 HTR2C (0.61) HTR2CHTR2AKDM4EMEN1TP53
Hydrochloric Acid SCHEMBL7001168 0.66 HTR2C (0.52) HTR2CHTR2AKDM4EMEN1TP53
SCHEMBL1752535 0.65 HTR1A (0.71) HTR1ADRD2
SCHEMBL5141708 0.65 HTR1A (0.71) HTR1ADRD2
SCHEMBL29462303 0.63 HTR2C (1.00) HTR2CHTR2AKDM4EMEN1TP53
SCHEMBL4352456 0.63 HTR2C (1.00) HTR2CHTR2AKDM4EMEN1TP53
SCHEMBL7669760 0.63 HTR2C (1.00) HTR2CHTR2AKDM4EMEN1TP53
SCHEMBL29407494 0.62 PARP1 (0.50) HTR2CHTR2AKDM4EMEN1TP53
SCHEMBL19305557 0.62 PARP1 (0.50) HTR2CHTR2AKDM4EMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250082685-A1 METHODS FOR ATTENUATING VIRAL INFECTION AND FOR TREATING LUNG INJURY Spiritus Therapeutics, Inc. (US) 2025-03-13 US claimed
CN-118485358-B Optimization configuration method for distributed blockchain production logistics resources based on improved teaching and learning algorithm 暨南大学 2025-02-07 CN claimed
CN-118485358-A Optimization configuration method for distributed blockchain production logistics resources based on improved teaching and learning algorithm 暨南大学 2024-08-13 CN claimed
WO-2023081299-A9 A PURIFIED ENRICHED POPULATION EXOSOMES DERIVED FROM INDIVIDUALS WITH A CHRONIC PROGRESSIVE LUNG DISEASE FOR NONINVASIVE DETECTION, STAGING, AND MEDICAL MONITORING OF DISEASE PROGRESSION Spiritus Therapeutics, Inc. (US) 2024-03-21 WO claimed
EP-4267958-A2 METHOD FOR SMALL-RNA BIOMARKER IDENTIFICATION AND FUNCTIONAL EVALUATION OF CIRCULATING EXTRACELLULAR VESICLES COMPRISING EXOSOMES Hackensack Meridian Health Center for Discovery and Innovation (US) 2023-11-01 EP claimed
WO-2023178169-A2 COMPOSITIONS AND METHODS FOR TREATING THE PATHOPHYSIOLOGY OF SEVERE VIRAL INFECTION ANEMOI BIOTECH HOLDINGS, INC. (US) 2023-09-21 WO claimed
WO-2023081299-A1 A PURIFIED ENRICHED POPULATION EXOSOMES DERIVED FROM INDIVIDUALS WITH A CHRONIC PROGRESSIVE LUNG DISEASE FOR NONINVASIVE DETECTION, STAGING, AND MEDICAL MONITORING OF DISEASE PROGRESSION Spiritus Therapeutics, Inc. (US) 2023-05-11 WO claimed
US-20230147720-A1 Purified Enriched Population Exosomes Derived From Individuals With A Chronic Progressive Lung Disease For Noninvasive Detection, Staging, And Medical Monitoring Of Disease Progression Spiritus Therapeutics, Inc. (US) 2023-05-11 US claimed
US-20220401477-A1 METHOD FOR CONTROLLING VIRAL INFECTIONS THROUGH ADOPTIVE TRANSFER OF A CELL PRODUCT COMPRISING AN EXPANDED AND ENRICHED POPULATION OF SUPERACTIVATED CYTOKINE KILLER CELLS VERDURE BIOTECH, INC. (US) 2022-12-22 US claimed
WO-2022245813-A2 A METHOD FOR CONTROLLING VIRAL INFECTIONS THROUGH ADOPTIVE TRANSFER OF A CELL PRODUCT COMPRISING AN EXPANDED AND ENRICHED POPULATION OF SUPERCTIVATED CYTOKINE KILLER CELLS VERDURE BIOTECH, INC. (US) 2022-11-24 WO claimed
WO-2022140662-A2 METHOD FOR SMALL-RNA BIOMARKER IDENTIFICATION AND FUNCTIONAL EVALUATION OF CIRCULATING EXTRACELLULAR VESICLES COMPRISING EXOSOMES Hackensack Meridian Health Center For Discovery and Innovation (US) 2022-06-30 WO claimed
EP-2308885-B1 Novel compounds and methods for therapy GILEAD SCIENCES INC (US) 2014-11-19 EP claimed
EP-2245037-B1 NOVEL COMPOUNDS AND METHODS FOR THERAPY GILEAD SCIENCES INC (US) 2014-06-18 EP claimed
EP-2308885-A2 Novel compounds and methods for therapy Gilead Sciences, Inc. (US) 2011-04-13 EP claimed
US-20090317418-A1 VACCINES AND METHODS FOR PREVENTION AND TREATMENT OF DRUG-RESISTANT HIV-1 AND HEPATITIS B VIRUS THE GOV'T OF USOA as represented by the SECRETARY OF THE DEPT OF HHS (US) 2009-12-24 US claimed
US-20090232768-A1 NOVEL COMPOUNDS AND METHODS FOR THERAPY GILEAD SCIENCES, INC. (US) 2009-09-17 US claimed
WO-2008134578-A2 SYNTHESIS OF OPTICALLY ACTIVE RADIO-LABELED REVERSE TRANSCRIPTASE INHIBITORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF (US) 2008-11-06 WO claimed
US-12607589-B2 Methods, assays and systems for detection of a target analyte SORRENTO THERAPEUTICS, INC. (US) 2026-04-21 US disclosed
WO-1993006106-A1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE IMIDAZO[4,5,1-jk][1,4]-BENZODIAZEPIN-2(1H^_)-THIONES JANSSEN PHARMACEUTICA N.V. (BE) 1993-04-01 WO disclosed
EP-0454427-A1 Antiretroviral bases Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic (CZ) 1991-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220401477-A1 METHOD FOR CONTROLLING VIRAL INFECTIONS THROUGH ADOPTIVE TRANSFER OF A CELL PRODUCT COMPRISING AN EXPANDED AND ENRICHED POPULATION OF SUPERACTIVATED CYTOKINE KILLER CELLS IFNG, PBK, IL4 HTR2C 3989/4885HTR2A 4388/4885KDM4E 3355/4885
US-12607589-B2 Methods, assays and systems for detection of a target analyte PRSS3, PRSS2, ZP1 HTR2C 3465/4885HTR2A 3764/4885KDM4E 4126/4885
US-20090232768-A1 NOVEL COMPOUNDS AND METHODS FOR THERAPY TP53, ZC3HAV1, ZFX HTR2C 4054/4885HTR2A 4056/4885KDM4E 1150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.