Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150842 | 0.89 | HCRTR2 (0.50) | LMNAKDM4ETP53MAPTHCRTR2 | |
| SCHEMBL29150850 | 0.89 | KMT2A (0.43) | HCRTR2KMT2AHSD11B1POLBHPGD | |
| SCHEMBL29150799 | 0.87 | HCRTR2 (0.40) | LMNAKDM4EMAPTHCRTR2KMT2A | |
| SCHEMBL29150833 | 0.86 | HSD11B1 (0.44) | LMNATP53HCRTR2KMT2AHSD11B1 | |
| SCHEMBL29150815 | 0.85 | TP53 (0.48) | LMNATP53MAPTKMT2AHPGD | |
| SCHEMBL29150830 | 0.84 | HCRTR2 (0.38) | HCRTR2KMT2AHSD11B1KCNJ6KCNJ5 | |
| SCHEMBL28293334 | 0.82 | TP53 (0.47) | LMNAKDM4ETP53MAPTHCRTR2 | |
| SCHEMBL29150838 | 0.76 | HSD11B1 (0.41) | LMNAKMT2AHSD11B1HPGD | |
| SCHEMBL29001236 | 0.75 | LMNA (0.41) | LMNAKDM4ETP53MAPTHCRTR2 | |
| SCHEMBL30354433 | 0.74 | HSP90AA1 (0.43) | LMNAKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947665-A | Synthetic method of alpha-aryl-beta-chloroamide | 湘潭大学 | 2023-04-11 | — | — | CN | disclosed |