Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150842 | 0.89 | HCRTR2 (0.50) | HCRTR2KMT2AHSD11B1LMNAALDH1A1 | |
| SCHEMBL29150850 | 0.89 | KMT2A (0.43) | HCRTR2KMT2AHSD11B1PTPN1NSD2 | |
| SCHEMBL29150792 | 0.87 | LMNA (0.46) | HCRTR2KMT2AHSD11B1LMNAPOLB | |
| SCHEMBL29150833 | 0.86 | HSD11B1 (0.44) | HCRTR2KMT2AHSD11B1PTPN1MEN1 | |
| SCHEMBL29150815 | 0.85 | TP53 (0.48) | KMT2ALMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29150830 | 0.84 | HCRTR2 (0.38) | HCRTR2KMT2AHSD11B1ALDH1A1SIRT2 | |
| SCHEMBL29150838 | 0.76 | HSD11B1 (0.41) | KMT2AHSD11B1MEN1LMNASMN1; SMN2 | |
| SCHEMBL6331211 | 0.74 | KCNA5 (0.43) | HCRTR2KMT2AHSD11B1PTPN1MEN1 | |
| SCHEMBL30354436 | 0.74 | HPGD (0.49) | KMT2ANR1I2MAOBPTPN1MEN1 | |
| SCHEMBL29150804 | 0.73 | ALDH1A1 (0.38) | HCRTR2HSD11B1TDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947665-A | Synthetic method of alpha-aryl-beta-chloroamide | 湘潭大学 | 2023-04-11 | — | — | CN | disclosed |