Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150842 | 0.86 | HCRTR2 (0.50) | HCRTR2KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL29150850 | 0.86 | KMT2A (0.43) | HCRTR2KMT2AHSD11B1KCNJ6KCNJ5 | |
| SCHEMBL29150799 | 0.84 | HCRTR2 (0.40) | HCRTR2KMT2AHSD11B1SIRT2ALDH1A1 | |
| SCHEMBL29150792 | 0.84 | LMNA (0.46) | HCRTR2KMT2AHSD11B1KCNJ6KCNJ5 | |
| SCHEMBL29150833 | 0.82 | HSD11B1 (0.44) | HCRTR2KMT2AHSD11B1ALDH1A1KEAP1 | |
| SCHEMBL29150815 | 0.81 | TP53 (0.48) | KMT2AALDH1A1HTT | |
| SCHEMBL30354428 | 0.76 | RORC (0.52) | KMT2ARORCKEAP1NFE2L2TAS2R14 | |
| SCHEMBL29150838 | 0.73 | HSD11B1 (0.41) | KMT2AHSD11B1RORCHTTNR1H3 | |
| SCHEMBL29150804 | 0.71 | ALDH1A1 (0.38) | HCRTR2HSD11B1ALDH1A1HTT | |
| SCHEMBL27470492 | 0.70 | KMT2A (0.54) | HCRTR2KMT2AHSD11B1ALDH1A1KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947665-A | Synthetic method of alpha-aryl-beta-chloroamide | 湘潭大学 | 2023-04-11 | — | — | CN | disclosed |