Triethylene Glycol

Triethylene Glycol

SCHEMBL2915086

C=CCOC(=O)OCC=C.OCCOCCOCCO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TSHR P16473 8/20 0.43
ALDH1A1 P00352 5/20 0.43
TP53 P04637 2/20 0.43
HIF1A Q16665 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.40
CYP3A4 P08684 2/20 0.37
MAPT P10636 2/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
THRB P10828 2/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentaethylene Glycol SCHEMBL2906371 1.00 MEN1 (0.46) MEN1KMT2ATSHRALDH1A1TP53
Tetraethylene Glycol SCHEMBL2912605 1.00 MEN1 (0.46) MEN1KMT2ATSHRALDH1A1TP53
Di(Hydroxyethyl)Ether SCHEMBL160804 0.98 TSHR (0.45) MEN1KMT2ATSHRALDH1A1TP53
SCHEMBL8976178 0.96 TSHR (0.45) MEN1KMT2ATSHRALDH1A1TP53
SCHEMBL3891820 0.96 TSHR (0.45) MEN1KMT2ATSHRALDH1A1TP53
Di(Hydroxyethyl)Ether SCHEMBL9405385 0.94 TSHR (0.42) MEN1KMT2ATSHRALDH1A1TP53
SCHEMBL11482671 0.93 TSHR (0.42) MEN1KMT2ATSHRALDH1A1TP53
Triethylene Glycol SCHEMBL7267483 0.92 MEN1 (0.42) MEN1KMT2ATSHRALDH1A1TP53
Di(Hydroxyethyl)Ether SCHEMBL27828483 0.90 TSHR (0.39) MEN1KMT2ATSHRALDH1A1TP53
Di(Hydroxyethyl)Ether SCHEMBL7266923 0.90 TSHR (0.42) MEN1KMT2ATSHRALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58040315-A None JP disclosed
US-11639413-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2023-05-02 US disclosed
US-20210017327-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS AND APPLICATION OF SAME MITSUI CHEMICALS, INC. (JP) 2021-01-21 US disclosed
EP-3724700-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS AND APPLICATION OF SAME Mitsui Chemicals, Inc. (JP) 2020-10-21 EP disclosed
US-20190284324-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS AND APPLICATION OF SAME MITSUI CHEMICALS, INC. (JP) 2019-09-19 US disclosed
EP-3527597-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2019-08-21 EP disclosed
WO-2019117305-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS AND APPLICATION OF SAME MITSUI CHEMICALS, INC. (JP) 2019-06-20 WO disclosed
US-8648130-B2 Resin composition, transparent member obtained from the resin composition, and use of the same MITSUI CHEMICALS, INC. (JP) 2014-02-11 US disclosed
US-20100256271-A1 RESIN COMPOSITION, TRANSPARENT MEMBER OBTAINED FROM THE RESIN COMPOSITION, AND USE OF THE SAME MITSUI CHEMICALS, INC. (JP) 2010-10-07 US disclosed
EP-2223969-A1 RESIN COMPOSITION, TRANSPARENT MEMBER OBTAINED FROM THE RESIN COMPOSITION, AND USE OF THE SAME Mitsui Chemicals, Inc. (JP) 2010-09-01 EP disclosed
US-7629433-B2 Odor-less during hydrolytic deblocking, separation; for use as source for aldehydes; crosslinking agents SIKA TECHNOLOGY AG (CH) 2009-12-08 US disclosed
US-20090176944-A1 Aldimines Comprising Reactive Groups Containing Active Hydrogen, and Use Thereof SIKA TECHNOLOGY AG (CH) 2009-07-09 US disclosed
US-20090099333-A1 Compounds Containing Aldimine SIKA TECHNOLOGY AG (CH) 2009-04-16 US disclosed
US-5730911-A Process for the manufacture of a substrate made of transparent organic glass and substrate thus obtained ESSILOR INTERNATIONAL-COMPAGNIE GENERAL D'OPTIQUE (FR) 1998-03-24 US disclosed
EP-0590573-B1 Resin for plastic lens HITACHI CHEMICAL CO LTD (JP) 1998-01-07 EP disclosed
US-5559200-A POLYMERIZING STYRENE, CYCLOALKYL ACRYLATE OR METHACRYLATE AND CROSSLINKING AGENT, MERCAPTAN OR A-METHYLSTYRENE DIMER MOLECULAR WEIGHT MODIFIER HITACHI CHEMICAL COMPANY, LTD. (JP) 1996-09-24 US disclosed
US-5449731-A Copolymer includes styrene, alicyclic (meth)acrylate, and polyfunctional monomers; transparent; edging ability, low specific gravity, high refractive index; eyeglasses HITACHI CHEMICAL COMPANY, LTD. (JP) 1995-09-12 US disclosed
EP-0590573-A2 Resin for plastic lens HITACHI CHEMICAL COMPANY, LTD. (JP) 1994-04-06 EP disclosed
JP-S5840315-A DYEABLE THERMOSETTING RESIN COMPOSITION MIZUNO KAKUGANKIYOU KK 1983-03-09 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090176944-A1 Aldimines Comprising Reactive Groups Containing Active Hydrogen, and Use Thereof ADH5, ADH1C, ADH1A MEN1 1107/4885KMT2A 2393/4885TSHR 4062/4885
US-20090099333-A1 Compounds Containing Aldimine ALDH7A1, ALDH3A1, ALDH1A1 MEN1 1496/4885KMT2A 2472/4885TSHR 4769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.