Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL25430864 | 0.98 | ALDH1A1 (0.35) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| SCHEMBL3265562 | 0.82 | MEN1 (0.39) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| SCHEMBL27705339 | 0.75 | ALDH1A1 (0.36) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| SCHEMBL28529359 | 0.75 | LMNA (0.37) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| Iodide SCHEMBL27475412 | 0.73 | ALDH1A1 (0.35) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| SCHEMBL8027987 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| SCHEMBL440580 | 0.71 | TYR (0.37) | ALDH1A1KCNH2MEN1KMT2ATDP1 | |
| SCHEMBL28572772 | 0.69 | ALDH1A1 (0.35) | ALDH1A1KCNH2MEN1KMT2ATSHR | |
| SCHEMBL8979881 | 0.68 | KCNH2 (0.46) | ALDH1A1KCNH2MEN1KMT2ATDP1 | |
| SCHEMBL15967965 | 0.68 | KCNH2 (0.46) | ALDH1A1KCNH2TDP1L3MBTL1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529502-A | CD38 chimeric co-stimulatory receptors and uses thereof | 纪念斯隆-凯特琳癌症中心 | 2024-02-06 | — | — | CN | disclosed |