SCHEMBL940609

SCHEMBL940609

NC(=O)c1ncn(C2O[C@H](C(O)P(=O)(O)O)[C@@H](O)[C@H]2O)c1N=CNC1O[C@H](C(O)P(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ATIC P31939 2/20 0.40
FBP1 P09467 1/20 0.39
KDM4E B2RXH2 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
HTT P42858 1/20 0.37
BLM P54132 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20298607 1.00 ATIC (0.40) ATICFBP1KDM4ETDP1ALDH1A1
SCHEMBL29140827 0.83
SCHEMBL29152304 0.81 ATIC (0.47) ATICFBP1KDM4ETDP1ALDH1A1
SCHEMBL22684942 0.79 ATIC (0.65) ATICFBP1KDM4ETDP1ALDH1A1
SCHEMBL938225 0.78 ATIC (0.60) ATICFBP1KDM4ETDP1ALDH1A1
SCHEMBL28773388 0.78 ATIC (0.47) ATICFBP1KDM4ETDP1ALDH1A1
SCHEMBL940486 0.77 ATIC (0.64) ATICFBP1KDM4ETDP1ALDH1A1
SCHEMBL850150 0.72 FBP1 (0.49) ATICFBP1KDM4ETDP1ALDH1A1
SCHEMBL2509891 0.68 ATIC (0.46) ATICFBP1KDM4ETDP1ALDH1A1
SCHEMBL4307801 0.66 KDM4E (0.56) ATICFBP1KDM4ETDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3989992-A2 THERAPEUTIC COMPOSITIONS AND METHODS OF USING SEROTONIN MODULATING MICROBIOME-BASED INTERVENTIONS TO TREAT SEROTONIN-RELATED DISEASES OR DISORDERS Holobiome, Inc. (US) 2022-05-04 EP claimed
WO-2020264390-A2 THERAPEUTIC COMPOSITIONS AND METHODS OF USING SEROTONIN MODULATING MICROBIOME-BASED INTERVENTIONS TO TREAT SEROTONIN-RELATED DISEASES OR DISORDERS HOLOBIOME, INC. (US) 2020-12-30 WO claimed
US-8494779-B2 Method for screening essential metabolites in growth of microorganisms KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-07-23 US claimed
US-20250368691-A1 Virulence Attenuated Bacteria Based Protein Delivery UNIV BASEL (CH) 2025-12-04 US disclosed
US-20250262254-A1 THERAPEUTIC COMPOSITIONS AND METHODS OF USING SEROTONIN MODULATING MICROBIOME-BASED INTERVENTIONS TO TREAT SEROTONIN-RELATED DISEASES OR DISORDERS HOLOBIOME, INC (US) 2025-08-21 US disclosed
US-20240165169-A1 Pharmaceutical Combinations for Treating Cancer T3 PHARMACEUTICALS AG (CH) 2024-05-23 US disclosed
US-20240165265-A1 Pharmaceutical Combinations for Treating Cancer T3 PHARMACEUTICALS AG (CH) 2024-05-23 US disclosed
CN-118006531-A Attenuated bacteria-based protein delivery 巴塞尔大学 2024-05-10 CN disclosed
CN-110325545-B Attenuated bacteria-based protein delivery 巴塞尔大学 2024-02-09 CN disclosed
EP-4313310-A1 PHARMACEUTICAL COMBINATIONS FOR TREATING CANCER T3 Pharmaceuticals AG (CH) 2024-02-07 EP disclosed
EP-4314036-A1 PHARMACEUTICAL COMBINATIONS FOR TREATING CANCER T3 Pharmaceuticals AG (CH) 2024-02-07 EP disclosed
US-10563174-B2 Proteins increasing pancreatic beta cell number and methods of use UNIVERSITY OF OREGON (US) 2020-02-18 US disclosed
US-20170292115-A1 PROTEINS INCREASING PANCREATIC BETA CELL NUMBER AND METHODS OF USE UNIVERSITY OF OREGON (US) 2017-10-12 US disclosed
US-7869957-B2 Methods and systems to identify operational reaction pathways THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-01-11 US disclosed
US-7635572-B2 Methods for conducting assays for enzyme activity on protein microarrays Life Technologies Corporation (US) 2009-12-22 US disclosed
EP-2098597-A1 Method for manufacturing L-amino acids using improved strains of the enterobacteriaceae family Evonik Degussa GmbH (DE) 2009-09-09 EP disclosed
EP-1642109-A4 METHODS FOR CONDUCTING ASSAYS FOR ENZYME ACTIVITY ON PROTEIN MICROARRAYS PROTOMETRIX INC (US) 2007-09-05 EP disclosed
EP-1642109-A2 METHODS FOR CONDUCTING ASSAYS FOR ENZYME ACTIVITY ON PROTEIN MICROARRAYS Protometrix, Inc. (US) 2006-04-05 EP disclosed
US-20050118665-A1 Methods for conducting assays for enzyme activity on protein microarrays PROTOMETRIX, INC. 2005-06-02 US disclosed
WO-2005003721-A2 ENZYME ACTIVITY ASSAYS ON PROTEIN MICROARRAYS PROTOMETRIX, INC. (US) 2005-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250262254-A1 THERAPEUTIC COMPOSITIONS AND METHODS OF USING SEROTONIN MODULATING MICROBIOME-BASED INTERVENTIONS TO TREAT SEROTONIN-RELATED DISEASES OR DISORDERS TPH1, TPH2, HTR1A ATIC 2448/4885FBP1 1850/4885KDM4E 3595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.