Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728419 | 0.94 | ALDH1A1 (0.53) | ALDH1A1HDAC8HDAC1HDAC6CYP1A2 | |
| SCHEMBL728203 | 0.94 | ALDH1A1 (0.67) | ALDH1A1CRBNGAACTSDPYGL | |
| SCHEMBL5679153 | 0.81 | ALDH1A1 (0.67) | ALDH1A1CRBNHDAC1GAACTSD | |
| SCHEMBL655826 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL328279 | 0.81 | ALDH1A1 (0.67) | ALDH1A1CRBNGAACTSDPYGL | |
| Hydrochloric Acid SCHEMBL2553196 | 0.80 | ALDH1A1 (0.51) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL13294935 | 0.79 | HDAC7 (0.53) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL5925494 | 0.78 | GAA (0.64) | ALDH1A1CRBNGAACTSDPYGL | |
| SCHEMBL570110 | 0.77 | GAA (0.61) | ALDH1A1GAAMAPTHSD17B10LMNA | |
| SCHEMBL224165 | 0.77 | ALDH1A1 (0.71) | ALDH1A1CRBNGAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222291-A2 | COMPOUNDS FOR THE SELECTIVE TREATMENT OF THE INTESTINAL IMMUNO-INFLAMMATORY COMPONENT OF THE CELIAC DISEASE | Giuliani International Limited (IE) | 2010-09-01 | — | — | EP | claimed |
| WO-2009080828-A2 | COMPOUNDS FOR THE SELECTIVE TREATMENT OF THE INTESTINAL IMMUNO-INFLAMMATORY COMPONENT OF THE CELIAC DISEASE | GIULIANI INTERNATIONAL LIMITED (IE) | 2009-07-02 | — | — | WO | claimed |