SCHEMBL5679153

SCHEMBL5679153

COc1cc(N)ccc1C(=O)NN

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.67
CTSD P07339 1/20 0.62
CRBN Q96SW2 1/20 0.52
GAA P10253 7/20 0.49
MAPT P10636 4/20 0.49
HTT P42858 2/20 0.49
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
TP53 P04637 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
KDM4E B2RXH2 2/20 0.45
HPGD P15428 2/20 0.44
POLB P06746 1/20 0.44
PYGL P06737 1/20 0.44
PKM P14618 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL328279 0.86 ALDH1A1 (0.67) ALDH1A1CTSDCRBNGAAMAPT
SCHEMBL728203 0.86 ALDH1A1 (0.67) ALDH1A1CTSDCRBNGAAMAPT
SCHEMBL3110944 0.85 ALDH1A1 (0.61) ALDH1A1CTSDCRBNGAAMAPT
SCHEMBL5925494 0.83 GAA (0.64) ALDH1A1CTSDCRBNGAAMAPT
SCHEMBL13733997 0.83 ALDH1A1 (0.58) ALDH1A1CRBNGAAMAPTHTT
SCHEMBL4939202 0.83 TP53 (0.66) ALDH1A1CTSDGAAMAPTHTT
SCHEMBL966735 0.83 CTSD (0.62) ALDH1A1CTSDGAAMAPTTSHR
SCHEMBL4333687 0.83 CTSD (0.67) ALDH1A1CTSDGAAMAPTHTT
SCHEMBL224165 0.82 ALDH1A1 (0.71) ALDH1A1CRBNGAAMAPTHTT
SCHEMBL3850604 0.82 ALDH1A1 (0.61) ALDH1A1CRBNMAPTMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119931076-B Method for synthesizing metal organic framework material by aqueous phase one-pot method JINAN UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-119931076-A Method for synthesizing metal organic framework material by aqueous phase one-pot method 暨南大学 2025-05-06 CN disclosed
EP-1652881-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers Rohm and Haas Company (US) 2006-05-03 EP disclosed
US-20060089436-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers AUSTEN STEVEN C 2006-04-27 US disclosed
US-4642322-A Stabilization of chlorine-containing thermoplastics with nitrogen-containing organic compounds CIBA-GEIGY CORPORATION (US) 1987-02-10 US disclosed