Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GRM5 | P41594 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343578 | 0.90 | ALDH1A1 (0.53) | ALDH1A1TSHRGRM5NPC1MAPK1 | |
| Hydrochloric Acid SCHEMBL8093613 | 0.87 | ALDH1A1 (0.59) | ALDH1A1TSHRGRM5NPC1RAB9A | |
| SCHEMBL4642422 | 0.85 | ALDH1A1 (0.45) | ALDH1A1TSHRGRM5NPC1RAB9A | |
| SCHEMBL29153306 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TSHRGRM5NPC1RAB9A | |
| SCHEMBL7664334 | 0.84 | ADAMTS5 (0.52) | ALDH1A1GRM5NPC1RAB9AKMT2A | |
| SCHEMBL11906738 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL476827 | 0.83 | TSHR (0.61) | ALDH1A1TSHRGRM5NPC1RAB9A | |
| SCHEMBL231282 | 0.83 | TSHR (0.61) | ALDH1A1TSHRGRM5NPC1RAB9A | |
| SCHEMBL29288482 | 0.82 | CA1 (0.49) | ALDH1A1GRM5NPC1RAB9AMAPK1 | |
| SCHEMBL11555946 | 0.81 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2118 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496175-A | TRADD inhibitor derivative and preparation method and application thereof | 安徽医科大学 | 2024-08-16 | — | — | CN | claimed |
| CN-107586291-B | A kind of synthetic method of razaxaban metabolin 5 | 梯尔希（南京）药物研发有限公司 | 2019-08-20 | — | — | CN | claimed |
| CN-107586291-A | A kind of synthetic method of razaxaban metabolin 5 | 梯尔希（南京）药物研发有限公司 | 2018-01-16 | — | — | CN | claimed |
| EP-1506176-B1 | AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PFIZER ITALIA SRL (IT) | 2013-04-24 | — | — | EP | claimed |
| US-7497951-B2 | Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and method for water treatment using the same | TORAY INDUSTRIES, INC. (JP) | 2009-03-03 | — | — | US | claimed |
| EP-1534675-B1 | FLUORO AND SULPHONYLAMINO CONTAINING 3,6-DISUBSTITUTED AZABICYCLO¬3.1.0 HEXANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LAB LTD (IN) | 2009-02-25 | — | — | EP | claimed |
| US-20070284309-A1 | Composite Semipermeable Membrane, Production Process Thereof, And Element, Fluid Separation Equipment And Method For Water Treatment Using The Same | TORAY INDUSTRIES, INC. (JP) | 2007-12-13 | — | — | US | claimed |
| US-7288562-B2 | Fluoro and sulphonylamino containing 3,6-disubstituted azabicyclo (3.1.0) hexane derivatives as muscarinic receptor antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2007-10-30 | — | — | US | claimed |
| EP-1819428-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND METHOD FOR WATER TREATMENT USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2007-08-22 | — | — | EP | claimed |
| WO-2006046781-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND METHOD FOR WATER TREATMENT USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2006-05-04 | — | — | WO | claimed |
| US-6407255-B2 | THERAPY FOR PSYCHOLOGICAL DISORDERS | MERCK SHARP & DOHME LTD. (GB) | 2002-06-18 | — | — | US | claimed |
| EP-1087966-B1 | CHEMICAL SYNTHESIS OF MORPHOLINE DERIVATIVES | MERCK SHARP & DOHME (GB) | 2002-05-08 | — | — | EP | claimed |
| EP-0678502-B1 | Process for preparing glycoloylanilides | CLARIANT GMBH (DE) | 1999-03-31 | — | — | EP | claimed |
| EP-0665858-B1 | PROCESS FOR PREPARING ALIPHATIC POLYESTERS | SHELL INT RESEARCH (NL) | 1998-01-21 | — | — | EP | claimed |
| US-5616799-A | REACTING A CORRESPONDING NITRO COMPOUND WITH A KETONE AND HYDROGEN IN PRESENCE OF A NOBLE METAL CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | claimed |
| JP-H08502313-A | — | — | 1996-03-12 | — | — | JP | claimed |
| EP-0665858-A1 | PROCESS FOR PREPARING ALIPHATIC POLYESTERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-08-09 | — | — | EP | claimed |
| US-5378797-A | Process for preparing aliphatic polyesters | SHELL OIL COMPANY (US) | 1995-01-03 | — | — | US | claimed |
| WO-1994009054-A1 | PROCESS FOR PREPARING ALIPHATIC POLYESTERS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-04-28 | — | — | WO | claimed |
| US-5095126-A | Efficient synthesis for optically pure stereogenically labile 4-substituted-2-hydroxytetronic acids | OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1992-03-10 | — | — | US | claimed |