Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29154224 | 0.77 | HTT (0.37) | LRRK2LMNAL3MBTL1 | |
| SCHEMBL29154210 | 0.71 | — | — | |
| SCHEMBL17144869 | 0.65 | LMNA (0.38) | LRRK2LMNACA12CA1CA2 | |
| SCHEMBL13729776 | 0.64 | HSD17B10 (0.36) | LRRK2CYP11B2LMNACA12CA1 | |
| SCHEMBL17144873 | 0.63 | LMNA (0.38) | LRRK2NPC1LMNACA12CA1 | |
| SCHEMBL30281248 | 0.61 | CYP11B2 (0.54) | LRRK2CYP11B2NPC1L3MBTL1ALDH1A1 | |
| SCHEMBL17828138 | 0.60 | CYP11B2 (0.46) | CYP11B2NPC1LMNAALDH1A1USP2 | |
| SCHEMBL12525153 | 0.57 | GPR119 (0.40) | LMNAL3MBTL1ALDH1A1USP2PDE10A | |
| SCHEMBL28488653 | 0.56 | CYP11B2 (0.51) | LRRK2CYP11B2NPC1ALDH1A1 | |
| SCHEMBL15184550 | 0.56 | HSD17B10 (0.43) | LMNAL3MBTL1PDE10ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203206-A | GCN2 modulating compounds and uses thereof | 希伯塞尔股份有限公司 | 2023-12-08 | — | — | CN | disclosed |