Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3187893 | 0.68 | LMNA (0.39) | HSD17B10LRRK2LMNACA12CA1 | |
| SCHEMBL13729778 | 0.67 | ALDH1A1 (0.35) | LMNAL3MBTL1MAPK10ALDH1A1 | |
| Formic Acid SCHEMBL5396644 | 0.65 | USP2 (0.40) | HSD17B10LMNAUSP2L3MBTL1ALDH1A1 | |
| SCHEMBL17144873 | 0.65 | LMNA (0.38) | HSD17B10LRRK2LMNACA12CA1 | |
| SCHEMBL4794245 | 0.64 | ALDH1A1 (0.45) | HSD17B10LRRK2USP2SYKALDH1A1 | |
| SCHEMBL5186125 | 0.64 | HSD17B10 (0.40) | HSD17B10LMNACA12CA1CA2 | |
| SCHEMBL29154209 | 0.64 | LRRK2 (0.35) | LRRK2PDE10ALMNACA12CA1 | |
| SCHEMBL23331024 | 0.64 | ALDH1A1 (0.41) | HSD17B10LMNAL3MBTL1CYP11B2ALDH1A1 | |
| SCHEMBL5221777 | 0.63 | ALDH1A1 (0.40) | HSD17B10LMNAUSP2ALDH1A1 | |
| SCHEMBL5384548 | 0.62 | PTPN11 (0.45) | HSD17B10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |