Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.44 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.44 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476911 | 0.92 | AKR1C3 (0.69) | AKR1C3DHODHTRPM8MCL1HTT | |
| SCHEMBL554744 | 0.92 | AKR1C3 (0.69) | AKR1C3DHODHTRPM8MCL1HTT | |
| SCHEMBL184192 | 0.86 | ALDH1A1 (0.59) | AKR1C3ALDH1A1TSHRESR1KDM4E | |
| SCHEMBL956428 | 0.86 | ALDH1A1 (0.59) | AKR1C3ALDH1A1TSHRESR1KDM4E | |
| SCHEMBL8462385 | 0.84 | SLC9A1 (0.54) | AKR1C3ALDH1A1KDM4ESLC9A1SLC9A3 | |
| SCHEMBL3863126 | 0.84 | SLC9A1 (0.54) | AKR1C3ALDH1A1KDM4ESLC9A1SLC9A3 | |
| SCHEMBL5830531 | 0.82 | AKR1C3 (0.52) | AKR1C3DHODHTRPM8MCL1HTT | |
| SCHEMBL5830527 | 0.82 | AKR1C3 (0.52) | AKR1C3DHODHTRPM8MCL1HTT | |
| SCHEMBL30977615 | 0.79 | HTT (0.60) | AKR1C3DHODHTRPM8MCL1HTT | |
| SCHEMBL4622685 | 0.77 | MAPT (0.51) | AKR1C3DHODHTRPM8HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117487811-A | Compositions and methods for treating complications and diseases associated with von willebrand factor | 邦德治疗有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-110520128-B | Compositions and methods for treating complications and diseases associated with von Willebrand Factor | 邦德治疗有限公司 | 2023-11-14 | — | — | CN | disclosed |