Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291583 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1KDM1AKDM4EATM | |
| SCHEMBL27474236 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1KDM1AKDM4EATM | |
| SCHEMBL1194994 | 0.83 | KDM4E (0.43) | ALDH1A1TDP1KDM1AKDM4EATM | |
| SCHEMBL28538742 | 0.83 | KDM4E (0.43) | ALDH1A1TDP1KDM1AKDM4EATM | |
| SCHEMBL2171776 | 0.82 | KDM1A (0.42) | ALDH1A1TDP1KDM1AKDM4EATM | |
| SCHEMBL15978312 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TDP1KDM1ACA2CACNA2D1 | |
| SCHEMBL11511816 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TDP1KDM1ACA2CACNA2D1 | |
| SCHEMBL11511817 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TDP1KDM1ACA2CACNA2D1 | |
| SCHEMBL15482735 | 0.78 | KDM4E (0.43) | KDM1AKDM4EATM | |
| 3-Methylbutanoic Acid SCHEMBL7036541 | 0.78 | KDM1A (0.46) | ALDH1A1TDP1KDM1AKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-10322995-B2 | Substituted cyano cycloalkyl penta-2,4-dienes, cyano cycloalkyl pent-2-en-4-ynes, cyano heterocyclyl penta-2,4-dienes and cyano heterocyclyl pent-2-en-4-ynes as active substances against abiotic plant stress | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-06-18 | — | — | US | disclosed |
| US-20170210701-A1 | SUBSTITUTED CYANO CYCLOALKYL PENTA-2,4-DIENES, CYANO CYCLOALKYL PENT-2-EN-4-YNES, CYANO HETEROCYCLYL PENTA-2,4-DIENES AND CYANO HETEROCYCLYL PENT-2-EN-4-YNES AS ACTIVE SUBSTANCES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-07-27 | — | — | US | disclosed |
| EP-2697193-B1 | SUBSTITUTED 5-(CYCLOHEX-2-EN-1-YL)-PENTA-2,4-DIENES AND 5-(CYCLOHEX-2-EN-1-YL)-PENT-2-EN-4-INES AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS | BAYER IP GMBH (DE) | 2016-07-06 | — | — | EP | disclosed |
| WO-2016012362-A1 | SUBSTITUTED CYANO CYCLOALKYL PENTA-2,4-DIENES, CYANO CYCLOALKYL PENT-2-EN-4-YNES, CYANO HETEROCYCLYL PENTA-2,4-DIENES AND CYANO HETEROCYCLYL PENT-2-EN-4-YNES AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-28 | — | — | WO | disclosed |
| US-9185914-B2 | Substituted 5-(cyclohex-2-en-1-yl)-penta-2,4-dienes and 5-(cyclohex-2-en-1-yl)-pent-2-en-4-ines as active agents against abiotic stress in plants | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| US-20140087949-A1 | SUBSTITUTED 5-(CYCLOHEX-2-EN-1-YL)-PENTA-2,4-DIENES AND 5-(CYCLOHEX-2-EN-1-YL)-PENT-2-EN-4-INES AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-27 | — | — | US | disclosed |
| US-20140051577-A1 | SUBSTITUTED 5-(BICYCLO[4.1.0]HEPT-3-EN-2-YL)PENTA-2,4-DIENES AND 5-(BICYCLO[4.1.0]HEPT-3-EN-2-YL)PENT-2-ENE-4-INES AS ACTIVE AGENTS AGAINST ABIOTIC STRESSES IN PLANTS | FRACKENPOHL JENS (DE) | 2014-02-20 | — | — | US | disclosed |
| US-8153848-B2 | Homoallyl alcohols useful as fragrances | GIVAUDAN SA (CH) | 2012-04-10 | — | — | US | disclosed |
| EP-2220019-B1 | HOMOALLYL ALCOHOLS USEFUL AS FRAGRANCES | GIVAUDAN SA (CH) | 2012-03-14 | — | — | EP | disclosed |
| EP-2220019-A1 | HOMOALLYL ALCOHOLS USEFUL AS FRAGRANCES | Givaudan SA (CH) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009065244-A1 | HOMOALLYL ALCOHOLS USEFUL AS FRAGRANCES | GIVAUDAN SA (CH) | 2009-05-28 | — | — | WO | disclosed |
| US-7238651-B2 | Process for preparing an overbased detergent | THE LUBRIZOL CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| EP-1694802-A1 | PROCESS FOR PREPARING AN OVERBASED DETERGENT | The Lubrizol Corporation (US) | 2006-08-30 | — | — | EP | disclosed |
| US-20060178278-A1 | Process for Preparing an Overbased Detergent | THE LUBRIZOL CORPORATION (US) | 2006-08-10 | — | — | US | disclosed |
| WO-2005042677-A1 | PROCESS FOR PREPARING AN OVERBASED DETERGENT | THE LUBRIZOL CORPORATION (US) | 2005-05-12 | — | — | WO | disclosed |
| EP-1227111-A1 | TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF | Yoshitomi Fine Chemicals, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |
| US-4774342-A | ANTITUMOR AGENTS | SUNTORY LIMITED (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0108645-B1 | NOVEL AILANTHONE DERIVATIVE | SUNTORY LIMITED (JP) | 1987-05-13 | — | — | EP | disclosed |
| EP-0108645-A2 | Novel ailanthone derivative | SUNTORY LIMITED (JP) | 1984-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210701-A1 | SUBSTITUTED CYANO CYCLOALKYL PENTA-2,4-DIENES, CYANO CYCLOALKYL PENT-2-EN-4-YNES, CYANO HETEROCYCLYL PENTA-2,4-DIENES AND CYANO HETEROCYCLYL PENT-2-EN-4-YNES AS ACTIVE SUBSTANCES | CBR3, NPY2R, CBR1 | ALDH1A1 1730/4885TDP1 2167/4885KDM1A 1824/4885 |
| US-20140087949-A1 | SUBSTITUTED 5-(CYCLOHEX-2-EN-1-YL)-PENTA-2,4-DIENES AND 5-(CYCLOHEX-2-EN-1-YL)-PENT-2-EN-4-INES AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS | ECH1, ENY2, CYCS | ALDH1A1 2749/4885TDP1 2570/4885KDM1A 1824/4885 |
| US-20140051577-A1 | SUBSTITUTED 5-(BICYCLO[4.1.0]HEPT-3-EN-2-YL)PENTA-2,4-DIENES AND 5-(BICYCLO[4.1.0]HEPT-3-EN-2-YL)PENT-2-ENE-4-INES AS ACTIVE AGENTS AGAINST ABIOTIC STRESSES IN PLANTS | RER1, ECH1, CYCS | ALDH1A1 2844/4885TDP1 3678/4885KDM1A 3540/4885 |
| US-20060178278-A1 | Process for Preparing an Overbased Detergent | DEGS1, ADH1C, CYP26B1 | ALDH1A1 983/4885TDP1 1631/4885KDM1A 628/4885 |
| US-10322995-B2 | Substituted cyano cycloalkyl penta-2,4-dienes, cyano cycloalkyl pent-2-en-4-ynes, cyano heterocyclyl penta-2,4-dienes and cyano heterocyclyl pent-2-en-4-ynes as active substances against abiotic plant stress | NPY2R, NPY1R, XPA | ALDH1A1 2790/4885TDP1 2647/4885KDM1A 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.