SCHEMBL291585

SCHEMBL291585

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nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 1/20 0.34
TRPA1 O75762 2/20 0.30
TRPM8 Q7Z2W7 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24024236 1.00 TLR4 (0.34) TLR4TRPA1TRPM8
SCHEMBL2684088 1.00 TLR4 (0.34) TLR4TRPA1TRPM8
Isopulegol SCHEMBL1868660 0.83 TRPA1 (0.33) TRPA1TRPM8
Menthol SCHEMBL8423507 0.82 TRPM8 (0.64) TRPA1TRPM8
SCHEMBL19021266 0.79 TLR4 (0.34) TLR4
SCHEMBL16230473 0.78 TLR4 (0.37) TLR4
SCHEMBL23924296 0.74 EPHX1 (0.46) TRPA1TRPM8
SCHEMBL27692448 0.71 TLR4 (0.34) TLR4
SCHEMBL19321816 0.70
SCHEMBL19321813 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12568998-B2 Flavouring composition with balanced taste profile SYMRISE AG (DE) 2026-03-10 US claimed
EP-4626972-A1 CONJUGATES OF POLYSACCHARIDES AND HYDROPHOBIC COMPOUNDS AS EMULSION STABILIZERS BASF SE (DE) 2025-10-08 EP claimed
EP-4444108-B1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-09-10 EP claimed
EP-4565194-A1 ODOR AND COLORANT STABILIZED COMPOSITIONS Symrise AG (DE) 2025-06-11 EP claimed
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 US claimed
CN-119744164-A Odor and colorant stable compositions 西姆莱斯股份公司 2025-04-01 CN claimed
US-20250059483-A1 PACKAGED CARBONATED ALCOHOLIC BEVERAGE CONTAINING GIN AND PRODUCTION METHOD THEREFOR SUNTORY HOLDINGS LIMITED (JP) 2025-02-20 US claimed
US-20250040580-A1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-02-06 US claimed
WO-2025026525-A1 HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS SYMRISE AG (DE) 2025-02-06 WO claimed
EP-4469439-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-12-04 EP claimed
EP-0918835-A1 RINSE ADDED FABRIC SOFTENING COMPOSITIONS AND METHOD OF USE FOR THE DELIVERY OF FRAGRANCE PRECURSORS THE PROCTER & GAMBLE COMPANY (US) 1999-06-02 EP claimed
US-5830835-A FABRIC SOFTENER, PERFUME ESTER MIXTURES PROCTER & GAMBLE COMPANY (US) 1998-11-03 US claimed
WO-1998027191-A1 RINSE-ADDED AND DRYER-ADDED FABRIC SOFTENING COMPOSITIONS AND METHOD OF USE FOR THE DELIVERY OF ESTER FRAGRANCE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1998-06-25 WO claimed
WO-1998027192-A2 DRYER ADDED FABRIC SOFTENING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-06-25 WO claimed
WO-1998027190-A1 DRYER-ACTIVATED FABRIC CONDITIONING AND ANTISTATIC COMPOSITIONS WITH IMPROVED PERFUME LONGEVITY THE PROCTER & GAMBLE COMPANY (US) 1998-06-25 WO claimed
WO-1998006803-A1 RINSE ADDED FABRIC SOFTENING COMPOSITIONS AND METHOD OF USE FOR THE DELIVERY OF FRAGRANCE PRECURSORS THE PROCTER & GAMBLE COMPANY (US) 1998-02-19 WO claimed
US-5668102-A SOLID OR LIQUID COMPOSITION CONTAINING CATIONIC QUATERNARY AMMONIUM FABRIC SOFTENING COMPOUND, NONIONIC OR ANIONIC ESTER OF NON-ALLYLIC ALCOHOL PERFUME THE PROCTER & GAMBLE COMPANY (US) 1997-09-16 US claimed
WO-1995007807-A2 METHODS AND COMPOSITIONS ADDRESSING SAPSTAIN, WOOD DEGRADATION, AND PESTS AFFECTING WOOD THE HORTICULTURE AND FOOD RESEARCH INSTITUTE OF NEW ZEALAND LIMITED (NZ) 1995-03-23 WO claimed
US-5230897-A Patch containing terpenes as penetration aid G. D. SEARLE & CO. (US) 1993-07-27 US claimed
WO-1993008798-A1 PENTADIMINE TRANSDERMAL COMPOSITION AND PATCH G.D. SEARLE & CO. (US) 1993-05-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12568998-B2 Flavouring composition with balanced taste profile TAS2R20, TAS2R50, TAS2R40 TLR4 3162/4885TRPA1 1619/4885TRPM8 1553/4885
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 TLR4 3995/4885TRPA1 185/4885TRPM8 152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.