Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 3/20 | 0.71 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.71 |
| ▸ | UGT1A3 | P35503 | 1/20 | 0.71 |
| ▸ | UGT1A8 | Q9HAW9 | 1/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.41 |
| ▸ | FOS | P01100 | 2/20 | 0.37 |
| ▸ | RXRG | P48443 | 4/20 | 0.34 |
| ▸ | RXRA | P19793 | 3/20 | 0.34 |
| ▸ | RXRB | P28702 | 3/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305411 | 0.88 | JUN (0.75) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL668045 | 0.85 | JUN (0.72) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL966228 | 0.85 | JUN (0.66) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2967226 | 0.84 | JUN (0.69) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL669409 | 0.84 | JUN (0.65) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL22528644 | 0.83 | JUN (1.00) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2956891 | 0.82 | JUN (0.67) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2960859 | 0.82 | JUN (0.69) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2960667 | 0.81 | JUN (0.68) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL1100281 | 0.80 | JUN (0.64) | JUNUGT1A1UGT1A3UGT1A8FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266557-B1 | COMBINATION OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND IMMUNOSUPPRESSING AGENT, AND PHARMACEUTICAL COMPOSITION COMPRISING THESE COMPONENTS | TOYAMA CHEMICAL CO LTD (JP) | 2013-08-14 | — | — | EP | claimed |
| EP-2022788-B1 | NOVEL CRYSTAL OF 3-[5-[4-(CYCLOPENTYLOXY)-2- HYDROXYBENZOYL]-2-[(3-HYDROXY-1,2-BENZISOXAZOL-6-YL)METHOXY]PHENYL]PROPIONIC ACID | TOYAMA CHEMICAL CO LTD (JP) | 2010-09-01 | — | — | EP | disclosed |