Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 3/20 | 0.65 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.65 |
| ▸ | UGT1A3 | P35503 | 1/20 | 0.65 |
| ▸ | UGT1A8 | Q9HAW9 | 1/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.42 |
| ▸ | FOS | P01100 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960312 | 0.92 | JUN (0.55) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL966228 | 0.91 | JUN (0.66) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL668045 | 0.86 | JUN (0.72) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL305411 | 0.84 | JUN (0.75) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2916013 | 0.84 | JUN (0.71) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2959732 | 0.83 | JUN (0.52) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2956891 | 0.82 | JUN (0.67) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2963281 | 0.82 | JUN (0.68) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2963278 | 0.82 | JUN (0.68) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2960667 | 0.81 | JUN (0.68) | JUNUGT1A1UGT1A3UGT1A8FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366544-A1 | REGULATION OF MUTANT TERT BY BRAF V600E/MAP KINASE PATHWAY THROUGH FOS/GABP IN HUMAN CANCER | UNIV JOHNS HOPKINS (US) | 2024-11-07 | — | — | US | claimed |
| US-11911356-B2 | Regulation of mutant TERT by BRAF V600E/map kinase pathway through FOS/GABP in human cancer | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-02-27 | — | — | US | claimed |
| US-20200323805-A1 | REGULATION OF MUTANT TERT BY BRAF V600E/MAP KINASE PATHWAY THROUGH FOS/GABP IN HUMAN CANCER | THE JOHNS HOPKINS UNIVERSITY | 2020-10-15 | — | — | US | claimed |
| EP-2258361-B1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNFalpha INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | TOYAMA CHEMICAL CO LTD (JP) | 2014-09-17 | — | — | EP | claimed |
| EP-2266557-B1 | COMBINATION OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND IMMUNOSUPPRESSING AGENT, AND PHARMACEUTICAL COMPOSITION COMPRISING THESE COMPONENTS | TOYAMA CHEMICAL CO LTD (JP) | 2013-08-14 | — | — | EP | claimed |
| EP-1445249-B1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-07 | — | — | EP | claimed |
| US-20120046326-A1 | DRUG CONTAINING BENZOPHENONE DERIVATIVE OR ITS SALT | TOYAMA CHEMICAL CO., LTD. (JP) | 2012-02-23 | — | — | US | claimed |
| US-20110039813-A1 | METHOD OF UTILIZATION OF COMBINATION OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND IMMUNOSUPPRESSING AGENT, AND PHARMACEUTICAL COMPOSITION COMPRISING THESE COMPONENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-02-17 | — | — | US | claimed |
| US-20110020366-A1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNF ALPHA INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-01-27 | — | — | US | claimed |
| EP-2266557-A1 | METHOD OF UTILIZATION OF COMBINATION OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND IMMUNOSUPPRESSING AGENT, AND PHARMACEUTICAL COMPOSITION COMPRISING THESE COMPONENTS | Toyama Chemical Co., Ltd. (JP) | 2010-12-29 | — | — | EP | claimed |
| EP-2258361-A1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNF INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | Toyama Chemical Co., Ltd. (JP) | 2010-12-08 | — | — | EP | claimed |
| US-20100240891-A1 | DRUG CONTAINING BENZOPHENONE DERIVATIVE OR ITS SALT | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-09-23 | — | — | US | claimed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | claimed |
| US-20250290152-A1 | GENETIC TRIO OF BRAF AND TERT MUTATIONS AND RS2853669TT IN PAPILLARY THYROID CANCER AGGRESSIVENESS | THE JOHNS HOPKINS UNIVERSITY | 2025-09-18 | — | — | US | disclosed |
| US-20240366544-A1 | REGULATION OF MUTANT TERT BY BRAF V600E/MAP KINASE PATHWAY THROUGH FOS/GABP IN HUMAN CANCER | UNIV JOHNS HOPKINS (US) | 2024-11-07 | — | — | US | disclosed |
| US-11911356-B2 | Regulation of mutant TERT by BRAF V600E/map kinase pathway through FOS/GABP in human cancer | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-02-27 | — | — | US | disclosed |
| US-20100240891-A1 | DRUG CONTAINING BENZOPHENONE DERIVATIVE OR ITS SALT | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-09-23 | — | — | US | disclosed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SHUNICHI SHIOZAWA (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1445249-A1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039813-A1 | METHOD OF UTILIZATION OF COMBINATION OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND IMMUNOSUPPRESSING AGENT, AND PHARMACEUTICAL COMPOSITION COMPRISING THESE COMPONENTS | SSB, NR3C2, BRPF3 | JUN 3882/4885UGT1A1 1141/4885UGT1A3 946/4885 |
| US-20100240891-A1 | DRUG CONTAINING BENZOPHENONE DERIVATIVE OR ITS SALT | SOST, MYD88, TRAF6 | JUN 528/4885UGT1A1 3139/4885UGT1A3 3682/4885 |
| US-20110020366-A1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNF ALPHA INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | TNF, NFKBIA, CHUK | JUN 1774/4885UGT1A1 2605/4885UGT1A3 3335/4885 |
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SP1, AP1G1, JUN | JUN 3/4885UGT1A1 1244/4885UGT1A3 2640/4885 |
| US-20120046326-A1 | DRUG CONTAINING BENZOPHENONE DERIVATIVE OR ITS SALT | SOST, MYD88, TRAF6 | JUN 528/4885UGT1A1 3139/4885UGT1A3 3682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.