Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 3/20 | 0.75 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.75 |
| ▸ | UGT1A3 | P35503 | 1/20 | 0.75 |
| ▸ | UGT1A8 | Q9HAW9 | 1/20 | 0.75 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.41 |
| ▸ | FOS | P01100 | 2/20 | 0.37 |
| ▸ | RXRG | P48443 | 4/20 | 0.34 |
| ▸ | RXRA | P19793 | 3/20 | 0.34 |
| ▸ | RXRB | P28702 | 3/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1100281 | 0.92 | JUN (0.64) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2967226 | 0.90 | JUN (0.69) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2916013 | 0.88 | JUN (0.71) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2964477 | 0.88 | JUN (0.59) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL668045 | 0.86 | JUN (0.72) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL22528644 | 0.86 | JUN (1.00) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL668828 | 0.85 | JUN (0.57) | JUNUGT1A1UGT1A3UGT1A8LMNA | |
| SCHEMBL966228 | 0.85 | JUN (0.66) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL30754698 | 0.84 | JUN (0.55) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL669409 | 0.84 | JUN (0.65) | JUNUGT1A1UGT1A3UGT1A8FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026354-A2 | METHODS AND COMPOSITIONS FOR USE IN TREATING AUTOSOMAL RECESSIVE POLYCYSTIC KIDNEY DISEASE (ARPKD) | THE GENERAL HOSPITAL CORPORATION (US) | 2024-02-01 | — | — | WO | claimed |
| US-20200129456-A1 | THERAPY FOR KINASE-DEPENDENT MALIGNANCIES | CHILDRENS HOSPITAL MED CT (US) | 2020-04-30 | — | — | US | claimed |
| US-20180360777-A1 | THERAPY FOR KINASE-DEPENDENT MALIGNANCIES | CHILDREN'S HOSPITAL MEDICAL CENTER | 2018-12-20 | — | — | US | claimed |
| US-20180125799-A1 | THERAPY FOR LEUKEMIA | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2018-05-10 | — | — | US | claimed |
| US-9877934-B2 | Therapy for leukemia | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2018-01-30 | — | — | US | claimed |
| US-20170079979-A1 | THERAPY FOR SOLID TUMORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-23 | — | — | US | claimed |
| WO-2015187496-A1 | THERAPY FOR SOLID TUMORS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2015-12-10 | — | — | WO | claimed |
| US-9066977-B2 | Method of utilization of combination of benzophenone derivative or salt thereof and immunosuppressing agent, and pharmaceutical composition comprising these components | TOYAMA CHEMICAL CO., LTD. (JP) | 2015-06-30 | — | — | US | claimed |
| US-9012482-B2 | Drug containing benzophenone derivative or its salt | TOYAMA CHEMICAL CO., LTD. (JP) | 2015-04-21 | — | — | US | claimed |
| EP-2258361-B1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNFalpha INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | TOYAMA CHEMICAL CO LTD (JP) | 2014-09-17 | — | — | EP | claimed |
| US-20110020366-A1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNF ALPHA INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-01-27 | — | — | US | claimed |
| EP-2266557-A1 | METHOD OF UTILIZATION OF COMBINATION OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND IMMUNOSUPPRESSING AGENT, AND PHARMACEUTICAL COMPOSITION COMPRISING THESE COMPONENTS | Toyama Chemical Co., Ltd. (JP) | 2010-12-29 | — | — | EP | claimed |
| EP-2258361-A1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNF INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | Toyama Chemical Co., Ltd. (JP) | 2010-12-08 | — | — | EP | claimed |
| US-20100240891-A1 | DRUG CONTAINING BENZOPHENONE DERIVATIVE OR ITS SALT | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-09-23 | — | — | US | claimed |
| EP-2022788-B1 | NOVEL CRYSTAL OF 3-[5-[4-(CYCLOPENTYLOXY)-2- HYDROXYBENZOYL]-2-[(3-HYDROXY-1,2-BENZISOXAZOL-6-YL)METHOXY]PHENYL]PROPIONIC ACID | TOYAMA CHEMICAL CO LTD (JP) | 2010-09-01 | — | — | EP | claimed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | claimed |
| US-20090275757-A1 | NOVEL CRYSTAL OF 3-[5-[4-(CYCLOPENTYLOXY)-2- HYDROXYBENZOYL]-2-[(3-HYDROXY-1,2-BENZISOXAZOL-6- YL)METHOXY]PHENYL]PROPIONIC ACID | TOYAMA CHEMICAL CO., LTD (JP) | 2009-11-05 | — | — | US | claimed |
| US-20090163562-A1 | ORAL COMPOSITION COMPRISING 3-[5-[4-(CYCLOPENTYLOXY) -2-HYDROXYBENZOYL]-2-[(3-HYDROXY-1,2-BENZISOXAZOL-6- YL)METHOXY]PHENYL]PROPIONIC ACID OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD (JP) | 2009-06-25 | — | — | US | claimed |
| EP-2022497-A1 | ORAL COMPOSITION COMPRISING 3-[5-[4-(CYCLOPENTYLOXY) -2-HYDROXYBENZOYL]-2-](3-HYDROXY-1,2-BENZISOXAZOL-6- YL)METHOXY¨PHENYL¨PROPIONIC ACID OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2009-02-11 | — | — | EP | claimed |
| EP-2022788-A1 | NOVEL CRYSTAL OF 3-Ý5-Ý4-(CYCLOPENTYLOXY)-2- HYDROXYBENZOYL¨-2-Ý(3-HYDROXY-1,2-BENZISOXAZOL-6- YL)METHOXY¨PHENYL¨PROPIONIC ACID | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-02-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275757-A1 | NOVEL CRYSTAL OF 3-[5-[4-(CYCLOPENTYLOXY)-2- HYDROXYBENZOYL]-2-[(3-HYDROXY-1,2-BENZISOXAZOL-6- YL)METHOXY]PHENYL]PROPIONIC ACID | HAO2, HAAO, HAO1 | JUN 2611/4885UGT1A1 1369/4885UGT1A3 1356/4885 |
| US-20100240891-A1 | DRUG CONTAINING BENZOPHENONE DERIVATIVE OR ITS SALT | SOST, MYD88, TRAF6 | JUN 528/4885UGT1A1 3139/4885UGT1A3 3682/4885 |
| US-20110020366-A1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNF ALPHA INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | TNF, NFKBIA, CHUK | JUN 1774/4885UGT1A1 2605/4885UGT1A3 3335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.