Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 3/20 | 0.66 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.66 |
| ▸ | UGT1A3 | P35503 | 1/20 | 0.66 |
| ▸ | UGT1A8 | Q9HAW9 | 1/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.42 |
| ▸ | FOS | P01100 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 4/20 | 0.34 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669409 | 0.91 | JUN (0.65) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL668045 | 0.88 | JUN (0.72) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2916013 | 0.85 | JUN (0.71) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL305411 | 0.85 | JUN (0.75) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2956891 | 0.83 | JUN (0.67) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2960312 | 0.83 | JUN (0.55) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2963281 | 0.83 | JUN (0.68) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2963278 | 0.83 | JUN (0.68) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2960667 | 0.83 | JUN (0.68) | JUNUGT1A1UGT1A3UGT1A8FFAR1 | |
| SCHEMBL2960859 | 0.82 | JUN (0.69) | JUNUGT1A1UGT1A3UGT1A8FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110020366-A1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNF ALPHA INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-01-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110020366-A1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNF ALPHA INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | TNF, NFKBIA, CHUK | JUN 1774/4885UGT1A1 2605/4885UGT1A3 3335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.