Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.56 |
| ▸ | CDK8 | P49336 | 1/20 | 0.56 |
| ▸ | NEK2 | P51955 | 1/20 | 0.56 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6411455 | 0.86 | CHEK1 (0.68) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL30828481 | 0.85 | CCNA2 (0.44) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL9910900 | 0.82 | CHEK1 (0.59) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL6416275 | 0.80 | MEN1 (0.58) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL29794663 | 0.76 | MPO (0.45) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL23320433 | 0.76 | MPO (0.49) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL30636856 | 0.76 | RIPK1 (0.51) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL2723759 | 0.76 | LCK (0.41) | GRM2KDM4EHPGDLMNASRC | |
| SCHEMBL23854775 | 0.75 | PARP1 (0.52) | DYRK1APARP1 | |
| SCHEMBL31457212 | 0.74 | CHEK1 (0.53) | CHEK1AURKACSNK1A1CDK8NEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385858-B | Photocatalytic preparation method of 2-phenyl-2H-indazole-3-carboxamide compound | 河南师范大学 | 2024-03-01 | — | — | CN | claimed |
| CN-115385858-B | Photocatalytic preparation method of 2-phenyl-2H-indazole-3-carboxamide compound | 河南师范大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-115385858-B | Photocatalytic preparation method of 2-phenyl-2H-indazole-3-carboxamide compound | 河南师范大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-115385858-B | Photocatalytic preparation method of 2-phenyl-2H-indazole-3-carboxamide compound | 河南师范大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-115385858-A | Photocatalytic preparation method of 2-phenyl-2H-indazole-3-formamide compound | 河南师范大学 | 2022-11-25 | — | — | CN | disclosed |