Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MPO | P05164 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | NEK2 | P51955 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6411455 | 0.82 | CHEK1 (0.68) | MEN1KMT2AMPOCHEK1AURKA | |
| SCHEMBL28643520 | 0.81 | MPO (0.49) | MEN1KMT2AMPOHPGDCHEK1 | |
| SCHEMBL29161027 | 0.80 | CHEK1 (0.56) | MEN1KMT2AMPOHPGDCHEK1 | |
| SCHEMBL1562180 | 0.80 | ALDH1A1 (0.49) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL30636856 | 0.78 | RIPK1 (0.51) | MEN1KMT2AMPOCHEK1AURKA | |
| SCHEMBL29092663 | 0.76 | BRD4 (0.47) | MEN1KMT2AMPOKDM4EPOLB | |
| SCHEMBL9161993 | 0.76 | HPGD (0.59) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL23320433 | 0.75 | MPO (0.49) | MEN1KMT2AMPOHPGDCHEK1 | |
| SCHEMBL22780224 | 0.75 | MPO (0.52) | KMT2AMPOHPGDALDH1A1MAPT | |
| SCHEMBL17111886 | 0.75 | HPGD (0.55) | MEN1KMT2AMPOHPGDCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020593-A1 | Aryl-heteroaromatic compounds, compositions comprising them and use | AVENTIS PHARMA (FR) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020593-A1 | Aryl-heteroaromatic compounds, compositions comprising them and use | TUBB3, TUBB, TUBB1 | MEN1 4042/4885KMT2A 2804/4885MPO 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.