Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468798 | 0.86 | AOC3 (0.57) | AOC3L3MBTL1ALDH1A1MAPTFFAR1 | |
| SCHEMBL3443782 | 0.83 | L3MBTL1 (0.67) | AOC3L3MBTL1ALDH1A1MAPTFFAR1 | |
| SCHEMBL27553229 | 0.82 | AOC3 (0.56) | AOC3L3MBTL1ALDH1A1MAPTCES2 | |
| SCHEMBL27553231 | 0.82 | AOC3 (0.56) | AOC3L3MBTL1ALDH1A1MAPTCES2 | |
| SCHEMBL24643324 | 0.82 | ALOX15 (0.57) | AOC3L3MBTL1ALDH1A1MAPTALOX15 | |
| SCHEMBL4811149 | 0.82 | ALOX15 (0.57) | AOC3L3MBTL1ALDH1A1MAPTALOX15 | |
| SCHEMBL4478666 | 0.81 | FFAR1 (0.56) | AOC3L3MBTL1ALDH1A1MAPTFFAR1 | |
| SCHEMBL4478662 | 0.81 | FFAR1 (0.56) | AOC3L3MBTL1ALDH1A1MAPTFFAR1 | |
| SCHEMBL3829766 | 0.78 | L3MBTL1 (0.62) | AOC3L3MBTL1ALDH1A1MAPTCES2 | |
| SCHEMBL29700753 | 0.77 | AOC3 (0.57) | AOC3L3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466780-A | Preparation method of (2S, 3R) -2-substituted amino-3-hydroxy-3- (4-methoxyphenyl) propionate | 科辉智药(深圳)新药研究中心有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-117466780-A | Preparation method of (2S, 3R) -2-substituted amino-3-hydroxy-3- (4-methoxyphenyl) propionate | 科辉智药(深圳)新药研究中心有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117466780-A | Preparation method of (2S, 3R) -2-substituted amino-3-hydroxy-3- (4-methoxyphenyl) propionate | 科辉智药(深圳)新药研究中心有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117466780-A | Preparation method of (2S, 3R) -2-substituted amino-3-hydroxy-3- (4-methoxyphenyl) propionate | 科辉智药(深圳)新药研究中心有限公司 | 2024-01-30 | — | — | CN | disclosed |