Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LDLR | P01130 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907837 | 0.90 | KDM4E (0.41) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL2915282 | 0.87 | MAPT (0.48) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL2915428 | 0.86 | RAB9A (0.40) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1530862 | 0.79 | DDB1 (0.46) | KDM4EMEN1KMT2AHDAC3HDAC8 | |
| SCHEMBL2910630 | 0.78 | MEN1 (0.46) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL2908369 | 0.76 | MAPT (0.37) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL3107879 | 0.75 | MAPT (0.52) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL2913996 | 0.75 | CA1 (0.43) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL2910562 | 0.75 | HPGD (0.41) | KDM4EMEN1KMT2AHTTNPC1 | |
| SCHEMBL2909795 | 0.74 | NR1H4 (0.39) | KDM4EMEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |