Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2916211 | 0.90 | KDM4E (0.36) | KDM4EMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL2910630 | 0.87 | MEN1 (0.46) | KDM4EMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL2915282 | 0.87 | MAPT (0.48) | MEN1KMT2AHTTALDH1A1LMNA | |
| SCHEMBL2915428 | 0.86 | RAB9A (0.40) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2912963 | 0.82 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1KCNK9LMNA | |
| SCHEMBL2910291 | 0.79 | CNR2 (0.38) | KDM4EMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL2913996 | 0.78 | CA1 (0.43) | KDM4EMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL1530854 | 0.78 | DDB1 (0.45) | KDM4EHTTALDH1A1POLBPLA2G1B | |
| SCHEMBL2907963 | 0.77 | GLRA3 (0.38) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3107879 | 0.75 | MAPT (0.52) | KDM4EMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |