Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910562 | 0.89 | HPGD (0.41) | RAB9ANPC1SMN1; SMN2NPSR1HPGD | |
| SCHEMBL2916211 | 0.86 | KDM4E (0.36) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL2907837 | 0.86 | KDM4E (0.41) | RAB9ANPC1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL2913166 | 0.85 | XDH (0.38) | RAB9ANPC1SMN1; SMN2NPSR1HPGD | |
| SCHEMBL2915282 | 0.83 | MAPT (0.48) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL2912524 | 0.83 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2NPSR1HPGD | |
| SCHEMBL2914837 | 0.81 | KMT2A (0.41) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL1530600 | 0.80 | AURKB (0.41) | RAB9ANPC1SMN1; SMN2NPSR1HPGD | |
| SCHEMBL2916119 | 0.80 | ALOX12 (0.37) | EPHX2NR1H4TRPV1ADRB1 | |
| SCHEMBL2909890 | 0.80 | CA1 (0.42) | RAB9ANPC1SMN1; SMN2NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |