SCHEMBL291628

SCHEMBL291628

O=C(O)c1ccccc1OS(=O)(=O)O.[NaH].[NaH]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.52
ALDH1A1 P00352 8/20 0.52
HSD17B10 Q99714 6/20 0.52
HPGD P15428 6/20 0.52
HMGB1 P09429 2/20 0.52
NAPRT Q6XQN6 2/20 0.52
ESR1 P03372 1/20 0.52
ITGB3 P05106 1/20 0.52
ITGA2B P08514 1/20 0.52
TSHR P16473 1/20 0.52
GGT1 P19440 1/20 0.52
PTGS1 P23219 1/20 0.52
PTGS2 P35354 1/20 0.52
BLM P54132 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MAPT P10636 2/20 0.50
USP2 O75604 1/20 0.50
PDE3A Q14432 1/20 0.50
HTT P42858 2/20 0.49
KMT2A Q03164 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6567084 1.00 KDM4E (0.52) KDM4EALDH1A1HSD17B10HPGDHMGB1
Sulfuric Acid SCHEMBL28096433 0.98 KDM4E (0.50) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL26647 0.98 KDM4E (0.53) KDM4EALDH1A1HSD17B10HPGDHMGB1
Water SCHEMBL3696220 0.96 KDM4E (0.52) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL20166760 0.96 KDM4E (0.52) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL3169153 0.96 KDM4E (0.52) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL7065758 0.96 KDM4E (0.52) KDM4EALDH1A1HSD17B10HPGDHMGB1
Ammonia Solution, Strong SCHEMBL10686252 0.96 KDM4E (0.52) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL8769958 0.96 KDM4E (0.52) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL6812015 0.96 KDM4E (0.52) KDM4EALDH1A1HSD17B10HPGDHMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210077639-A1 RADIOPHARMACEUTICAL PRODUCTS GE HEALTHCARE LTD (GB) 2021-03-18 US claimed
US-10328164-B2 Radiopharmaceutical products GE HEALTHCARE LIMITED (GB) 2019-06-25 US claimed
CN-1331081-A Tetraphosphine quatorphosphonium salt, its preparing process, and two-step tetraphosphine medicine kit and its application UNIV BEIJING NORMAL (CN) 2002-01-16 CN claimed
US-20260102523-A1 PHARMACEUTICAL COMPOSITION COMPRISING TETROFOSMIN AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF JUBILANT DRAXIMAGE INC (CA) 2026-04-16 US disclosed
US-12440583-B2 Pharmaceutical composition comprising tetrofosmin and pharmaceutically acceptable salts thereof JUBILANT DRAXIMAGE, INC. (CA) 2025-10-14 US disclosed
US-20250312364-A1 METHODS FOR THE USE OF PSYCHEDELICS TRYP THERAPEUTICS INC. (CA) 2025-10-09 US disclosed
CN-118831183-A Stabilized compositions of radionuclides and uses thereof 瑞择生物公司 2024-10-25 CN disclosed
US-20240307420-A1 IMPROVED METHODS FOR THE USE OF PSYCHEDELICS TRYP THERAPEUTICS INC. (CA) 2024-09-19 US disclosed
CN-118103078-A Stabilized compositions of radionuclides and uses thereof 瑞择生物公司 2024-05-28 CN disclosed
EP-3592735-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF TETROFOSMIN OR ACID ADDITION SALT THEREOF JUBILANT GENERICS LTD FORMERLY A DIVISION OF JUBILANT LIFE SCIENCES LTD (IN) 2024-03-20 EP disclosed
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FIRST WAVE BIO, INC. 2024-03-07 US disclosed
US-20090297442-A1 RADIOPHARMACEUTICAL PRODUCTS GE HEALTHCARE LIMITED (GB) 2009-12-03 US disclosed
EP-1345630-B1 STABILISED RADIOPHARMACEUTICAL COMPOSITIONS GE HEALTHCARE LTD (GB) 2008-11-05 EP disclosed
EP-1824525-B1 STABILISED 99mTC COMPOSITIONS GE HEALTHCARE LTD (GB) 2008-04-16 EP disclosed
EP-1824525-A1 STABILISED 99mTC COMPOSITIONS GE Healthcare Limited (GB) 2007-08-29 EP disclosed
WO-2006064175-A1 STABILISED 99mTC COMPOSITIONS GE HEALTHCARE LIMITED (GB) 2006-06-22 WO disclosed
US-7052672-B2 Stabilized radiopharmaceutical compositions GE HEALTHCARE LIMITED (GB) 2006-05-30 US disclosed
EP-1345630-A1 STABILISED RADIOPHARMACEUTICAL COMPOSITIONS GE Healthcare Limited (GB) 2003-09-24 EP disclosed
WO-2002053192-A1 STABILISED RADIOPHARMACEUTICAL COMPOSITIONS AMERSHAM PLC (GB) 2002-07-11 WO disclosed
CN-1331081-A Tetraphosphine quatorphosphonium salt, its preparing process, and two-step tetraphosphine medicine kit and its application UNIV BEIJING NORMAL (CN) 2002-01-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090297442-A1 RADIOPHARMACEUTICAL PRODUCTS MVD, TRHDE, EEF1E1 KDM4E 1252/4885ALDH1A1 3402/4885HSD17B10 3747/4885
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FH, CS, ECHS1 KDM4E 2452/4885ALDH1A1 2174/4885HSD17B10 528/4885
US-20210077639-A1 RADIOPHARMACEUTICAL PRODUCTS MVD, TRHDE, EEF1E1 KDM4E 1252/4885ALDH1A1 3402/4885HSD17B10 3747/4885
US-10328164-B2 Radiopharmaceutical products MVD, TRHDE, EEF1E1 KDM4E 1252/4885ALDH1A1 3402/4885HSD17B10 3747/4885
US-20260102523-A1 PHARMACEUTICAL COMPOSITION COMPRISING TETROFOSMIN AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF TREH, CD68, THPO KDM4E 3636/4885ALDH1A1 4433/4885HSD17B10 4328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.