SCHEMBL29163752

SCHEMBL29163752

FC(F)(F)c1ccc(I)c(I)c1I

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.37
CES2 O00748 1/20 0.30
GLA P06280 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11521981 0.82 NOTUM (0.31) NOTUM
SCHEMBL7926711 0.78 KIF11 (0.34) NOTUMCES2
SCHEMBL8499174 0.77 KDM4E (0.37) POLBGAA
SCHEMBL23114231 0.74 CA2 (0.33) TSHR
SCHEMBL16554018 0.74 NOTUM (0.37) NOTUMCES2GLAPOLBGAA
SCHEMBL31124641 0.72
SCHEMBL797108 0.72
SCHEMBL7597167 0.72 ALDH1A1 (0.39) POLBGAATSHR
SCHEMBL17520293 0.72 PDE2A (0.38) NOTUM
SCHEMBL30730977 0.72 PDE2A (0.38) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117327257-A Benzo tri (five-membered) heterocyclyl mono (di) alkyne bridged conjugated porous polymer and preparation method and application thereof 湘潭大学 2024-01-02 CN disclosed