Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 11/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2917635 | 0.76 | HRH3 (0.49) | — | |
| SCHEMBL2062784 | 0.69 | HTT (0.41) | — | |
| SCHEMBL2061657 | 0.69 | HTT (0.41) | — | |
| SCHEMBL2479144 | 0.68 | DRD1 (0.35) | — | |
| SCHEMBL2060771 | 0.68 | HTT (0.46) | — | |
| SCHEMBL2915586 | 0.68 | DRD1 (0.35) | — | |
| SCHEMBL2915008 | 0.67 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL2060974 | 0.67 | ALDH1A1 (0.47) | — | |
| SCHEMBL3007732 | 0.66 | IDO1 (0.41) | — | |
| SCHEMBL20061133 | 0.66 | HTT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2684874-B1 | Fused bicyclic derivatives of 2,4-diaminopyrimidine as alk and C-met inhibitors | CEPHALON INC (US) | 2017-05-17 | — | — | EP | disclosed |
| EP-2222647-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | Cephalon, Inc. (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2008051547-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2008-05-02 | — | — | WO | disclosed |