SCHEMBL29167679

SCHEMBL29167679

CCC1C=CC=CC1(c1ccccn1)c1ccccc1O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 1/20 0.33
NR3C1 P04150 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29167684 0.87 NPSR1 (0.36) SLC6A2
SCHEMBL29167626 0.86 TRPA1 (0.33)
SCHEMBL29167645 0.86 PSEN1 (0.32)
SCHEMBL29167671 0.86 CASP6 (0.32) SLC6A2SLC6A4NR3C1
SCHEMBL29167680 0.84 KMT2A (0.40)
SCHEMBL29167663 0.84 CYP2D6 (0.32)
SCHEMBL29167744 0.84 CNR1 (0.35)
SCHEMBL29167659 0.84 L3MBTL1 (0.39) SLC6A2NR3C1
SCHEMBL29167667 0.84 TRPV3 (0.35)
SCHEMBL29167563 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624029-A Arylpyridine or arylpiperidine derivative or salt thereof, synthesis and application and medicine 赣江中药创新中心 2024-03-01 CN disclosed